{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T09:41:22Z","timestamp":1792489282826,"version":"4.5.0"},"reference-count":43,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T00:00:00Z","timestamp":1792108800000},"content-version":"vor","delay-in-days":15,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Influenza Resp Viruses"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Globally, RSV declined to historically low levels following stay\u2010at\u2010home orders in 2020 and re\u2010emerged as restrictions lifted, with large inter\u2010seasonal outbreaks and other shifts in epidemiology. The effect of the pandemic restrictions on genomic diversity has not been well studied.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Individuals with respiratory symptoms were enrolled into community\u2010based surveillance studies and provided nasal swabs over three respiratory virus seasons from 2019 to 2022 in the Seattle metropolitan area in Washington State, USA. Samples were tested for RSV by RT\u2010qPCR, with whole genome sequencing performed for a subset.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Among children and adults, respectively, 1.8% (232\/13,014) and 0.2% (86\/46,042) of samples tested positive for RSV\u2010A and 1.1% (139\/13016) and 0.3% (119\/46043) for RSV\u2010B. Positive cases were observed in childcare (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200939), clinic (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u2009270), university (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200920), workplace (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200932) or nursing facility (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u20091) sites and through at\u2010home self\u2010administered testing (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u2009253). Median age for all participants was 33\u2009years (IQR: 23, 48) and 3\u2009years (IQR: 3, 33) for those who tested positive. Cough (\u2265\u200985%) and rhinorrhea (\u2265\u200985%) were the most common symptoms for RSV cases. During 2019\u20132020, six RSV\u2010A and three RSV\u2010B lineages circulated (majority lineages\n                      <jats:sc>A.D<\/jats:sc>\n                      .1 and B.D.4.1.1). Almost no RSV was detected during 2020\u20132021. During 2021\u20132022, RSV\u2010B lineage B.D.E.1 was dominant.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In a community surveillance study spanning several years, RSV was commonly detected in young children across several sites. Circulation of RSV was disrupted by pandemic mitigation measures, with shifts in genomic diversity detected after lifting of pandemic restrictions.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/irv.70332","type":"journal-article","created":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T01:20:50Z","timestamp":1792200050000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["RSV Molecular Epidemiology Pre\u2010 and Post\u2010COVID\u201019 Pandemic Periods in Seattle, Washington, USA"],"prefix":"10.1111","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4567-8232","authenticated-orcid":false,"given":"Pavitra","family":"Roychoudhury","sequence":"first","affiliation":[{"name":"Vaccine and Infectious Disease Division Fred Hutchinson Cancer Center  Seattle Washington USA"},{"name":"Department of Laboratory Medicine and Pathology University of Washington  Seattle Washington 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