{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T10:19:10Z","timestamp":1776766750489,"version":"3.51.2"},"reference-count":30,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2013,7,16]],"date-time":"2013-07-16T00:00:00Z","timestamp":1373932800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["International Wound Journal"],"published-print":{"date-parts":[[2015,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Negative pressure wound therapy (<jats:styled-content style=\"fixed-case\">NPWT<\/jats:styled-content>) has emerged as a cutting\u2010edge technology and provides an alternative solution to the problem of wounds. This study was undertaken to assess the efficacy of this technique in the treatment of chronic wounds. A prospective clinical study was used to evaluate our experience in use of <jats:styled-content style=\"fixed-case\">NPWT<\/jats:styled-content> in the healing of pressure ulcers and chronic wounds over 2 years. The primary end point of the study group was the time taken for appearance of healthy granulation tissue and full reepithelialisation without drainage. All patients with sepsis were excluded from the study. The statistical analysis of the data was carried out. Of the 60 patients studied, 41 had associated comorbidities including diabetes mellitus. The commonest site of occurrence was the lower limb. Coverage in the form of a flap was required at presentation in 63\u00b733% of patients. However, after initiation of <jats:styled-content style=\"fixed-case\">NPWT<\/jats:styled-content>, none of them required the procedure and they healed spontaneously either by secondary intention or by skin grafting. The time taken for appearance of healthy granulation tissue was 14\u00b736 \u00b1 4\u00b724 days. Complete healing of wounds occurred by 33\u00b71 \u00b1 10\u00b722 days. There was a statistically significant difference in the volume of the wounds before and after the intervention (<jats:italic>P<\/jats:italic> = 0\u00b7000). Complications resulting from <jats:styled-content style=\"fixed-case\">NPWT<\/jats:styled-content> were minimal. This technique is an excellent adjunct to surgical debridement.<\/jats:p>","DOI":"10.1111\/iwj.12132","type":"journal-article","created":{"date-parts":[[2013,7,16]],"date-time":"2013-07-16T04:58:37Z","timestamp":1373950717000},"page":"436-442","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":30,"title":["Negative pressure wound therapy as an adjunct in healing of chronic wounds"],"prefix":"10.1111","volume":"12","author":[{"given":"Vijay","family":"Langer","sequence":"first","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery Army Hospital (Research and Referral)  New Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Prem S","family":"Bhandari","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery Army Hospital (Research and Referral)  New Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Satyamoorthy","family":"Rajagopalan","sequence":"additional","affiliation":[{"name":"Department of Surgery Armed Forces Medical College  Pune India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mrinal K","family":"Mukherjee","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery Army Hospital (Research and Referral)  New Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,7,16]]},"reference":[{"key":"e_1_2_5_2_1","first-page":"901","volume-title":"Plastic surgery","author":"Hansen SL","year":"2006"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0094-1298(20)32468-8"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000637-199706000-00002"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000637-199706000-00001"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.12968\/jowc.2003.12.1.26451"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.2165\/00128071-200506030-00005"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.prs.0000222562.60260.f9"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cps.2007.07.005"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjps.2011.06.001"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.12968\/jowc.1999.8.2.25844"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1080\/713796078"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.ta.0000241150.15342.da"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(05)67695-7"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0b013e31818237ac"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.prs.0000225470.42514.8f"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.prs.0000299268.51008.47"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1067-1927.2004.12105.x"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/dmrr.861"},{"key":"e_1_2_5_20_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.106.621854"},{"key":"e_1_2_5_21_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1524-475X.2003.11503.x"},{"key":"e_1_2_5_22_1","first-page":"64","article-title":"Outcomes of sub\u2010atmospheric pressure dressing therapy on wounds of the diabetic foot","volume":"48","author":"Armstrong DG","year":"2002","journal-title":"Ostomy Wound Manage"},{"key":"e_1_2_5_23_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10016-003-0065-3"},{"key":"e_1_2_5_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1742-481X.2007.00317.x"},{"key":"e_1_2_5_25_1","doi-asserted-by":"publisher","DOI":"10.12968\/bjon.2003.12.Sup2.11324"},{"key":"e_1_2_5_26_1","first-page":"17","article-title":"Vacuum\u2010assisted closure: a method of facilitating wound healing","volume":"19","author":"Hutchinson L","year":"1999","journal-title":"World Counc Enteros Ther J"},{"key":"e_1_2_5_27_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006527-200504000-00004"},{"key":"e_1_2_5_28_1","unstructured":"EvansD LandL. Topical negative pressure for treating chronic wounds. The Cochrane Library Issue 1. Chichester: Wiley 2004."},{"key":"e_1_2_5_29_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005131-200501000-00011"},{"key":"e_1_2_5_30_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000637-200111000-00014"},{"key":"e_1_2_5_31_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-200110000-00013"}],"container-title":["International Wound Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fiwj.12132","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/iwj.12132","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T22:22:16Z","timestamp":1696198936000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/iwj.12132"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,7,16]]},"references-count":30,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2015,8]]}},"alternative-id":["10.1111\/iwj.12132"],"URL":"https:\/\/doi.org\/10.1111\/iwj.12132","archive":["Portico"],"relation":{},"ISSN":["1742-4801","1742-481X"],"issn-type":[{"value":"1742-4801","type":"print"},{"value":"1742-481X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,7,16]]},"assertion":[{"value":"2013-03-14","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2013-06-14","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2013-07-16","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}