{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,21]],"date-time":"2026-02-21T13:48:01Z","timestamp":1771681681981,"version":"3.50.1"},"reference-count":13,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2015,12,21]],"date-time":"2015-12-21T00:00:00Z","timestamp":1450656000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"LifeCell Corporation"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["International Wound Journal"],"published-print":{"date-parts":[[2016,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Biological alternatives to synthetic meshes are increasingly utilised in complex abdominal wall reconstruction. There is a lack of evidence demonstrating that non\u2010cross\u2010linked porcine acellular dermal matrix vascularizes and integrates with human tissue in suboptimal wound conditions. We aimed to evaluate these properties in Strattice\u2122 (Life Cell Inc., Branchburg, <jats:styled-content style=\"fixed-case\">NJ<\/jats:styled-content>) following ventral hernia repair. A retrospective review of patients with high\u2010risk ventral hernia repair utilising Strattice\u2122 as an onlay after open component separation was conducted. Patients with postoperative wound exploration and exposure of the onlay were included in this review. One patient underwent punch biopsy for histological analysis. Eleven patients with wound complications necessitating postoperative debridement and exposure of Strattice\u2122 onlay were identified. The onlay was partially debrided in two cases, and one case required complete excision. Vascularisation was clinically evident in 10 of 11 cases (91%) as demonstrated by the presence of granulation tissue and\/or the ability to support a skin graft. Histological analysis of one onlay 3 months postoperatively showed neovascularisation and collagen remodelling with minimal inflammatory response. Strattice\u2122 demonstrated resistance to rejection, ability to undergo vascularisation and incorporation into host tissues in sub\u2010optimal wound conditions following ventral hernia repair.<\/jats:p>","DOI":"10.1111\/iwj.12558","type":"journal-article","created":{"date-parts":[[2015,12,21]],"date-time":"2015-12-21T08:06:40Z","timestamp":1450685200000},"page":"972-976","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Porcine acellular dermal matrix (PADM) vascularises after exposure in open necrotic wounds seen after complex hernia repair"],"prefix":"10.1111","volume":"13","author":[{"given":"Arvind U","family":"Gowda","sequence":"first","affiliation":[{"name":"Division of Plastic Surgery University of Maryland School of Medicine  Baltimore MD USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarah M.","family":"Chang","sequence":"additional","affiliation":[{"name":"Division of Plastic Surgery University of Maryland School of Medicine  Baltimore MD USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karan","family":"Chopra","sequence":"additional","affiliation":[{"name":"Division of Plastic Surgery University of Maryland School of Medicine  Baltimore MD USA"},{"name":"Department of Plastic Surgery The Johns Hopkins University Hospital  Baltimore MD USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jamil A","family":"Matthews","sequence":"additional","affiliation":[{"name":"Division of Plastic Surgery University of Maryland School of Medicine  Baltimore MD USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jennifer","family":"Sabino","sequence":"additional","affiliation":[{"name":"Division of Plastic Surgery University of Maryland School of Medicine  Baltimore MD USA"},{"name":"Department of Plastic Surgery The Johns Hopkins University Hospital  Baltimore MD USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeffrey A","family":"Stromberg","sequence":"additional","affiliation":[{"name":"Division of Plastic Surgery University of Maryland School of Medicine  Baltimore MD USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hamid R","family":"Zahiri","sequence":"additional","affiliation":[{"name":"Division of Plastic Surgery University of Maryland School of Medicine  Baltimore MD USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joel","family":"Pinczewski","sequence":"additional","affiliation":[{"name":"Division of Plastic Surgery University of Maryland School of Medicine  Baltimore MD USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"III","given":"Luther H","family":"Holton","sequence":"additional","affiliation":[{"name":"Division of Plastic Surgery University of Maryland School of Medicine  Baltimore MD USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ronald P","family":"Silverman","sequence":"additional","affiliation":[{"name":"Division of Plastic Surgery University of Maryland School of Medicine  Baltimore MD USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Devinder P","family":"Singh","sequence":"additional","affiliation":[{"name":"Division of Plastic Surgery Anne Arundel Medical Center  Annapolis MD USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,12,21]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1177\/1090820X11418090"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.prs.0000254347.36092.9c"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.prs.0000204567.28952.9d"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.dental.2009.03.007"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.prs.0000302505.43942.07"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/GOX.0000000000000036"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0b013e3182818a3d"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.2217\/17460751.4.2.185"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1615\/JLongTermEffMedImplants.v15.i5.70"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjsurg.2012.05.031"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/SAP.0b013e31822f997b"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0b013e3181a3f595"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1089\/ten.tea.2008.0384"}],"container-title":["International Wound Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fiwj.12558","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/iwj.12558","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T21:45:48Z","timestamp":1696196748000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/iwj.12558"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,12,21]]},"references-count":13,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2016,10]]}},"alternative-id":["10.1111\/iwj.12558"],"URL":"https:\/\/doi.org\/10.1111\/iwj.12558","archive":["Portico"],"relation":{},"ISSN":["1742-4801","1742-481X"],"issn-type":[{"value":"1742-4801","type":"print"},{"value":"1742-481X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,12,21]]},"assertion":[{"value":"2015-07-07","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2015-11-22","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2015-12-21","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}