{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T16:40:42Z","timestamp":1785516042997,"version":"3.56.0"},"reference-count":25,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2016,4,29]],"date-time":"2016-04-29T00:00:00Z","timestamp":1461888000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["International Wound Journal"],"published-print":{"date-parts":[[2017,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The effective management of post\u2010operative wounds is important to prevent potential complications such as surgical\u2010site infections and wound dehiscence. The purpose of this study was to treat wound dehiscence in elderly patients who were subjected to orthopaedic surgical interventions. The dehisced wounds were treated with autologous micro\u2010grafts obtained using a promising <jats:styled-content style=\"fixed-case\">CE<\/jats:styled-content>\u2010certified medical device called Rigeneracons. This instrument is a biological disruptor of human tissues able to specifically select progenitor cells that, as already reported in previous studies, maintain high cell viability but mainly have a high regenerative potential, allowing the repair of damaged tissues. Autologous micro\u2010grafts obtained by Rigeneracons are ready to use and can be applied alone or in combination with biological scaffolds directly on the injured area. We observed in our patients a complete remission of dehisced wounds, on average, after 30 days from micro\u2010grafts application and a total wound re\u2010epithelialisation after 1 year from the surgical intervention. In conclusion, although we reported only three patients, autologous micro\u2010grafts can be considered a promising approach for the treatment of dehisced wounds, improving the wound\u2010healing process and in general the patient's quality of life without using other dressings.<\/jats:p>","DOI":"10.1111\/iwj.12601","type":"journal-article","created":{"date-parts":[[2016,4,30]],"date-time":"2016-04-30T13:03:28Z","timestamp":1462021408000},"page":"277-281","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":54,"title":["Rigenera protocol in the treatment of surgical wound dehiscence"],"prefix":"10.1111","volume":"14","author":[{"given":"Marco","family":"Marcarelli","sequence":"first","affiliation":[{"name":"Santa Croce Hospital, Unit of Orthopedics and Traumatology of Chieri and Moncalieri  Turin Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Letizia","family":"Trovato","sequence":"additional","affiliation":[{"name":"Human Brain Wave srl  Turin Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elvio","family":"Novarese","sequence":"additional","affiliation":[{"name":"Santa Croce Hospital, Unit of Orthopedics and Traumatology of Chieri and Moncalieri  Turin Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michele","family":"Riccio","sequence":"additional","affiliation":[{"name":"Plastic and Reconstructive Surgery, AOU \u201cOspedali Riuniti\u201d  Ancona Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Graziano","sequence":"additional","affiliation":[{"name":"SHRO Center of Biotechnology Temple University  Philadelphia PA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,4,29]]},"reference":[{"key":"e_1_2_6_2_1","first-page":"867","article-title":"Post\u2010operative wound management","volume":"42","author":"Yao K","year":"2013","journal-title":"Aust Fam Physician"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jocn.2015.01.009"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1513\/pats.200808-094GO"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anuro.2007.08.007"},{"key":"e_1_2_6_6_1","first-page":"369","article-title":"Post\u2010operative peritonitis due to anastomotic dehiscence after colonic resection. 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