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Its consequences lead to ulceration, disfigurement and even death, and it has reached epidemic proportions in several regions of the world. We describe a series of patients treated for <jats:styled-content style=\"fixed-case\">FMARs<\/jats:styled-content> in a specialised wound care centre and a thorough review of the literature. A retrospective chart review was performed from January 1999 to September 2015 of patients who had been injected with non\u2010medical foreign agents and who developed cutaneous ulceration needing treatment at the dermatology wound care centre. This study involved 23 patients whose ages ranged from 22 to 67 years with higher proportion of women and homosexual men. The most commonly injected sites were the buttocks (38\u00b75%), legs (18%), thighs (15\u00b74%) and breasts (11\u00b78%). Mineral oil (39%) and other unknown substances (30\u00b74%) were the most commonly injected. The latency period ranged from 1 week to 17 years. Complications included several skin changes such as sclerosis and ulceration as well as systemic complications. <jats:styled-content style=\"fixed-case\">FMAR<\/jats:styled-content> is a severe syndrome that may lead to deadly complications, and is still very common in Latin America.<\/jats:p>","DOI":"10.1111\/iwj.12643","type":"journal-article","created":{"date-parts":[[2016,8,4]],"date-time":"2016-08-04T06:55:13Z","timestamp":1470293713000},"page":"546-554","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":32,"title":["A case series and a review of the literature on foreign modelling agent reaction: an emerging problem"],"prefix":"10.1111","volume":"14","author":[{"given":"Ashley A","family":"Mart\u00ednez\u2010Villarreal","sequence":"first","affiliation":[{"name":"Department of Dermatology, Interdisciplinary Wound and Ostomy Care Center \u201cDr. Manuel Gea Gonzalez\u201d General Hospital  Mexico City 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