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This prospective study evaluated the performance of a composite wound dressing containing collagen\/oxidised regenerated cellulose in the treatment of medium\u2010depth (0\u00b74\u2009mm) DSWs in 25 multi\u2010morbid patients with chronic leg ulcers requiring STSG. The range of patients' ages was 44\u201384 years (mean 71\u00b76\u2009years) with DSW sizes ranging between 12 and 162\u2009cm<jats:sup>2<\/jats:sup> (mean 78\u2009cm<jats:sup>2<\/jats:sup>). Comorbidities included anticoagulation therapy (15 patients), anaemia (11 patients), diabetes (6 patients) and methicillin\u2010resistant <jats:italic>Staphylococcus aureus<\/jats:italic> (<jats:styled-content style=\"fixed-case\">MRSA<\/jats:styled-content>) ulcer colonisation (6 patients). The first dressing change was performed after 10\u2009days. Complete reepithelialisation was observed between the 10th and 34th day (mean 17\u00b72, median 14 days). Postoperative medium to strong bleeding occurred in only five patients (four with anticoagulation). Wound pain levels one day after harvesting were only moderate (range 0\u20131\u00b75, mean 0\u00b75, median 0\u00b75 on a six\u2010item scale). No wound infection was observed during the first dressing. The composite dressing used allowed for the fast healing of medium\u2010depth DSWs with minimal or no postoperative pain and bleeding in older multi\u2010morbid patients under anticoagulation treatment.<\/jats:p>","DOI":"10.1111\/iwj.12698","type":"journal-article","created":{"date-parts":[[2016,12,1]],"date-time":"2016-12-01T05:50:06Z","timestamp":1480571406000},"page":"791-800","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Effectiveness of collagen\/oxidised regenerated cellulose\/silver\u2010containing composite wound dressing for the treatment of medium\u2010depth split\u2010thickness skin graft donor site wounds in multi\u2010morbid patients: a prospective, non\u2010comparative, single\u2010centre study"],"prefix":"10.1111","volume":"14","author":[{"given":"Alexander","family":"Konstantinow","sequence":"first","affiliation":[{"name":"Department of Dermatology and Allergology Biederstein Technical University Munich  Munich Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tatjana V","family":"Fischer","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Allergology Biederstein Technical University Munich  Munich Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johannes","family":"Ring","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Allergology Biederstein Technical University Munich  Munich Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,12]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/wrr.12387"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/iwj.12387"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2014.04.049"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-475X.2009.00543.x"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/wrr.12394"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(98)70081-7"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/iwj.12575"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.1997.tb00666.x"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-540-29316-3_114"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-194412000-00006"},{"key":"e_1_2_5_12_1","first-page":"e45","article-title":"Do functional keratin dressings accelerate epithelialization in human partial thickness wounds? 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