{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T09:23:58Z","timestamp":1761989038698},"reference-count":29,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2017,3,1]],"date-time":"2017-03-01T00:00:00Z","timestamp":1488326400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["International Wound Journal"],"published-print":{"date-parts":[[2017,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>We report a 53\u2010year\u2010old female patient presenting with a refractory venous leg ulcer and unremarkable findings in the doppler Ultrasound venous mapping of the leg veins. Further comprehensive diagnostics demonstrated an underlying May\u2013Thurner syndrome. After resolution of the primary mechanical obstruction, rapid wound healing in the following 3 weeks was documented. Iliac vein compression syndrome, commonly known as May\u2013Thurner syndrome, is a distinguishable anatomical variant that results from an external compression over the left iliac vein exerted by the overriding adjacent right common iliac artery. It is mostly seen among young, healthy female patients and can easily be under\u2010diagnosed. Lower extremities duplex ultrasonography remains the gold standard in diagnosing venous insufficiency, but it should not solely depend on it. Instead, clinicians should consider other possibilities, assessing the patency within the truncal veins, which in turn might contribute to the venous insufficiency along the lower limbs. An active early diagnostic approach can prevent significant overall morbidity and help patients to ease back into their daily\u2010life activities. Therefore, it is recommended that all patients with suspected venous insufficiency and normal lower limbs duplex findings should undergo further evaluation of the truncal venous system pattern. May\u2013Thurner syndrome, along with other causes of iliac veins compression, should be considered in the differential diagnosis in unclear persistent cases of unilateral venous symptoms.<\/jats:p>","DOI":"10.1111\/iwj.12724","type":"journal-article","created":{"date-parts":[[2017,3,2]],"date-time":"2017-03-02T04:56:40Z","timestamp":1488430600000},"page":"578-582","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["May\u2013Thurner syndrome: an often overlooked cause for refractory venous leg ulcers"],"prefix":"10.1111","volume":"14","author":[{"given":"Maryam","family":"Alkhater","sequence":"first","affiliation":[{"name":"Department of Dermatology, Venerology and Allergology University Hospital of Essen  Essen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Finja","family":"Jockenh\u00f6fer","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Venerology and Allergology University Hospital of Essen  Essen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ingo","family":"Stoffels","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Venerology and Allergology University Hospital of Essen  Essen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joachim","family":"Dissemond","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Venerology and Allergology University Hospital of Essen  Essen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,3]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/iwj.12387"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1177\/000331979704800111"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.12968\/jowc.2014.23.12.601"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.12968\/jowc.2005.14.2.26732"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00105-016-3761-y"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1742-481X.2010.00660.x"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0037-1617353"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1610-0387.2010.07535.x"},{"key":"e_1_2_9_10_1","first-page":"310","article-title":"Chronic ulcers of the leg: a study of prevalence in a Scottish community","volume":"41","author":"Dale JJ","year":"1983","journal-title":"Health Bull"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.1800780729"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF03166911"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/iwj.12216"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0741-5214(95)70050-1"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1177\/000331975700800505"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01960918"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000441-190803000-00004"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.1800521028"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-8703(43)90285-6"},{"key":"e_1_2_9_20_1","first-page":"152","article-title":"Ultrasonographic diagnosis of iliac vein compression (May\u2010Thurner) syndrome","volume":"13","author":"Oguzkurt L","year":"2007","journal-title":"Diagn Interv Radiol"},{"key":"e_1_2_9_21_1","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1177\/000313480006600710","article-title":"Iliac vein compression syndrome: a new method of treatment","volume":"66","author":"Baron HC","year":"2000","journal-title":"Am Surg"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1259\/bjr.20130284"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1051-0443(07)61823-5"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvir.2007.09.007"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.apmr.2008.11.006"},{"key":"e_1_2_9_26_1","first-page":"490","article-title":"The place of duplex scanning for varicose veins and common venous problems","volume":"78","author":"Campbell WB","year":"1996","journal-title":"Ann R Coll Surg Engl"},{"key":"e_1_2_9_27_1","first-page":"283","article-title":"The impact of duplex scanning on vascular practice","volume":"15","author":"Androulakis AE","year":"1996","journal-title":"Int Angiol"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.1800831016"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvn.2004.12.001"},{"key":"e_1_2_9_30_1","first-page":"740182","article-title":"May\u2010Thurner syndrome: a case report and review of the literature","volume":"2013","author":"Kalu S","year":"2013","journal-title":"Case Rep Vasc Med"}],"container-title":["International Wound Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fiwj.12724","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/iwj.12724","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,2]],"date-time":"2023-10-02T16:55:51Z","timestamp":1696265751000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/iwj.12724"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,3]]},"references-count":29,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2017,6]]}},"alternative-id":["10.1111\/iwj.12724"],"URL":"https:\/\/doi.org\/10.1111\/iwj.12724","archive":["Portico"],"relation":{},"ISSN":["1742-4801","1742-481X"],"issn-type":[{"value":"1742-4801","type":"print"},{"value":"1742-481X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,3]]},"assertion":[{"value":"2016-11-01","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-01-25","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-03-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}