{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T06:17:07Z","timestamp":1783577827449,"version":"3.55.0"},"reference-count":38,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2017,8,2]],"date-time":"2017-08-02T00:00:00Z","timestamp":1501632000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"Perfuse Medtec, Inc. London"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["International Wound Journal"],"published-print":{"date-parts":[[2017,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>This evaluation involves an innovative muscle pump\u2010activating device (geko\u2122) as an adjunctive therapy with best practices for non\u2010healing venous leg ulcers (<jats:styled-content style=\"fixed-case\">VLUs<\/jats:styled-content>). Stimulating the common peroneal nerve (at the fibular head), the geko\u2122 device creates a response that acts as foot and calf muscle pumps, increasing venous, arterial and microcirculatory flow. The aim was to evaluate and determine if the geko\u2122 is effective in this population and if it should be added to the medical supply formulary. In all, 12 patients with 18 recalcitrant <jats:styled-content style=\"fixed-case\">VLUs<\/jats:styled-content> (defined as less than 30% reduction in wound size in 30 days with best practices) in two community settings in Ontario consented to the evaluation and were treated with the geko\u2122 for up to 20 weeks.<\/jats:p><jats:p>A total of 44% of wounds healed, and 39% decreased in size. One patient non\u2010adherent with the geko\u2122 and best practices had deterioration in his or her wounds. With the patients as their own control, the mean weekly healing rate with the geko\u2122 was 9\u00b735% (\u00b1<jats:styled-content style=\"fixed-case\">SD<\/jats:styled-content> 0\u00b710) compared to 0\u00b706% (\u00b1<jats:styled-content style=\"fixed-case\">SD<\/jats:styled-content> 0\u00b710) prior to baseline, which was statistically significant (<jats:italic>P<\/jats:italic> &lt; 0\u00b701). Three patients not in optimal therapy increased compression due to decreased pain, further enabling healing. This study was not a randomised investigation, although the patients acted as their own controls. A pragmatic evaluation reflects the reality of the community sector; in spite of best practices or evidence\u2010based care, therapy is not uniformly applied, with some participants unable to tolerate or indeed comply with optimal compression therapy. Rash occurred under the devices in 7 of 12 (58%) patients. One patient stopped the device due to rash, while another had to take breaks from using the device. Subsequently, the manufacturer (<jats:styled-content style=\"fixed-case\">FirstKind<\/jats:styled-content> Ltd) has developed a new device and protocol specific to the requirements of wound therapy to minimise this response.<\/jats:p><jats:p>This small case series demonstrated the highly significant effectiveness of the geko\u2122 device in these hard\u2010to\u2010heal <jats:styled-content style=\"fixed-case\">VLUs<\/jats:styled-content>. Further evaluations to determine dose and patient selection criteria are underway.<\/jats:p>","DOI":"10.1111\/iwj.12784","type":"journal-article","created":{"date-parts":[[2017,8,3]],"date-time":"2017-08-03T03:22:50Z","timestamp":1501730570000},"page":"1189-1198","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Evaluation of a muscle pump\u2010activating device for non\u2010healing venous leg ulcers"],"prefix":"10.1111","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6775-1031","authenticated-orcid":false,"given":"Connie","family":"Harris","sequence":"first","affiliation":[{"name":"CarePartners (formerly) Perfuse Medtec Inc.  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