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In the routine clinical approach, it is necessary to find new risk factors and end up with a quick and easy assessment of DFIs. In this study, we aimed to evaluate the independent risk factors for osteomyelitis, amputation and major amputation in patients with DFI using standard scoring procedures.<\/jats:p><jats:p>We prospectively studied 379 patients with <jats:styled-content style=\"fixed-case\">DFI<\/jats:styled-content>. The variables were analysed using logistic analysis. A total of 126 cases (33\u00b72%) underwent amputation. The odds ratios in the amputation model were 3\u00b709 for osteomyelitis (<jats:italic>P<\/jats:italic> &lt; 0\u00b7001), 4\u00b790 for arterial stenosis (<jats:styled-content style=\"fixed-case\">AS<\/jats:styled-content>) (<jats:italic>P<\/jats:italic> &lt; 0\u00b7001), 3\u00b767 for the history of <jats:styled-content style=\"fixed-case\">DFI<\/jats:styled-content> (<jats:italic>P<\/jats:italic> = 0\u00b7001), 2\u00b747 for ulcer duration &gt;60 days (<jats:italic>P<\/jats:italic> = 0\u00b7001), 3\u00b710 for ulcer depth &gt; 15 mm (<jats:italic>P<\/jats:italic> &lt; 0\u00b7001) and 10\u00b728 for fungal DFI (<jats:italic>P<\/jats:italic> = 0\u00b7015).<\/jats:p><jats:p>In this study, the unusual result of well\u2010known literature was fungal DFI as an independent risk factor for amputation in patients with DFI.<\/jats:p>","DOI":"10.1111\/iwj.12788","type":"journal-article","created":{"date-parts":[[2017,7,19]],"date-time":"2017-07-19T13:04:34Z","timestamp":1500469474000},"page":"1219-1224","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":49,"title":["Risk factors for amputation in patients with diabetic foot infection: a prospective study"],"prefix":"10.1111","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4294-5999","authenticated-orcid":false,"given":"Serhat","family":"Uysal","sequence":"first","affiliation":[{"name":"Department of Infectious Diseases and Clinical Microbiology Ege University Medical Faculty  Izmir Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bilgin","family":"Arda","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases and Clinical Microbiology Ege University Medical Faculty  Izmir Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meltem I","family":"Ta\u015fbakan","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases and Clinical Microbiology Ege University Medical Faculty  Izmir Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u015eevki","family":"\u00c7etinkalp","sequence":"additional","affiliation":[{"name":"Department of Endocrinology and Metabolism Ege University Medical Faculty  Izmir Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ilg\u0131n Y","family":"\u015eim\u015fir","sequence":"additional","affiliation":[{"name":"Department of Endocrinology and Metabolism Ege University Medical Faculty  Izmir Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"An\u0131l M","family":"\u00d6zt\u00fcrk","sequence":"additional","affiliation":[{"name":"Department of Orthopedics and Traumatology Ege University Medical Faculty  Izmir 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