{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T07:01:25Z","timestamp":1791442885317,"version":"4.3.3"},"reference-count":37,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2017,12,15]],"date-time":"2017-12-15T00:00:00Z","timestamp":1513296000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Acelity, Gatwick, West Sussex, UK"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["International Wound Journal"],"published-print":{"date-parts":[[2018,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    The aim of this study was to estimate the patterns of care and annual levels of health care resource use attributable to managing venous leg ulcers (VLUs) in clinical practice by the\n                    <jats:styled-content style=\"fixed-case\">UK<\/jats:styled-content>\n                    's National Health Service (\n                    <jats:styled-content style=\"fixed-case\">NHS<\/jats:styled-content>\n                    ) and the associated costs of patient management. This was a retrospective cohort analysis of the records of 505 patients in The Health Improvement Network (\n                    <jats:styled-content style=\"fixed-case\">THIN<\/jats:styled-content>\n                    ) Database. Patients' characteristics, wound\u2010related health outcomes and health care resource use were quantified, and the total\n                    <jats:styled-content style=\"fixed-case\">NHS<\/jats:styled-content>\n                    cost of patient management was estimated at 2015\/2016 prices. Overall, 53% of all\n                    <jats:styled-content style=\"fixed-case\">VLUs<\/jats:styled-content>\n                    healed within 12 months, and the mean time to healing was 3\u00b70 months. 13% of patients were never prescribed any recognised compression system, and 78% of their wounds healed. Of the 87% who were prescribed a recognised compression system, 52% of wounds healed. Patients were predominantly managed in the community by nurses with minimal clinical involvement of specialist clinicians. Up to 30% of all the\n                    <jats:styled-content style=\"fixed-case\">VLUs<\/jats:styled-content>\n                    may have been clinically infected at the time of presentation, and only 22% of patients had an ankle brachial pressure index documented in their records. The mean\n                    <jats:styled-content style=\"fixed-case\">NHS<\/jats:styled-content>\n                    cost of wound care over 12 months was an estimated \u00a37600 per\n                    <jats:styled-content style=\"fixed-case\">VLU<\/jats:styled-content>\n                    . However, the cost of managing an unhealed\n                    <jats:styled-content style=\"fixed-case\">VLU<\/jats:styled-content>\n                    was 4\u00b75 times more than that of managing a healed\n                    <jats:styled-content style=\"fixed-case\">VLU<\/jats:styled-content>\n                    (\u00a33000 per healed\n                    <jats:styled-content style=\"fixed-case\">VLU<\/jats:styled-content>\n                    and \u00a313 500 per unhealed\n                    <jats:styled-content style=\"fixed-case\">VLU<\/jats:styled-content>\n                    ). This study provides important insights into a number of aspects of\n                    <jats:styled-content style=\"fixed-case\">VLU<\/jats:styled-content>\n                    management in clinical practice that have been difficult to ascertain from other studies and provides the best estimate available of\n                    <jats:styled-content style=\"fixed-case\">NHS<\/jats:styled-content>\n                    resource use and costs with which to inform policy and budgetary decisions.\n                  <\/jats:p>","DOI":"10.1111\/iwj.12814","type":"journal-article","created":{"date-parts":[[2017,12,16]],"date-time":"2017-12-16T05:44:00Z","timestamp":1513403040000},"page":"29-37","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":181,"title":["Venous leg ulcer management in clinical practice in the UK: costs and outcomes"],"prefix":"10.1111","volume":"15","author":[{"given":"Julian F","family":"Guest","sequence":"first","affiliation":[{"name":"Catalyst Health Economics Consultants  Rickmansworth UK"},{"name":"Faculty of Life Sciences and Medicine King's College  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Graham W","family":"Fuller","sequence":"additional","affiliation":[{"name":"Catalyst Health Economics Consultants  Rickmansworth UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Vowden","sequence":"additional","affiliation":[{"name":"Bradford Teaching Hospitals NHS Foundation Trust, Bradford, UK and University of Bradford  Bradford UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,12,15]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1177\/153100350501700406"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1067\/mjd.2002.121739"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra055289"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2012.02.060"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1024\/0301-1526\/a000335"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.annepidem.2004.05.015"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9343(00)00379-X"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.12968\/bjcn.2010.15.Sup1.46906"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.7748\/ns2012.05.26.38.42.c9111"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2015-009283"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/iwj.12603"},{"key":"e_1_2_7_13_1","unstructured":"FletcherJ MoffattC PartschH VowdenK VowdenP. 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