{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T22:38:39Z","timestamp":1792190319030,"version":"4.4.0"},"reference-count":19,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2019,8,12]],"date-time":"2019-08-12T00:00:00Z","timestamp":1565568000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["International Wound Journal"],"published-print":{"date-parts":[[2019,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Closed incision negative pressure wound therapy (CINPWT) has been shown to be clinically effective compared with the traditional gauze dressing, reducing surgical site infections and wound complications. We evaluated the effect of CINPWT compared with gauze dressing on the need for revision surgery and survival after non\u2010traumatic major lower amputation. We included 309 patients undergoing 403 major lower amputations in a retrospective study from January 1, 2010 to November 23, 2017. A total of 139 patients received CINPWT, and 170 patients received stump bandage. There was no statistically significant difference between the two groups regarding the need for revision surgery (<jats:italic>P<\/jats:italic> =\u2009.45). Fourteen stump bandage patients and 15 CINPWT patients died in hospital (<jats:italic>P<\/jats:italic> =\u2009.57). One year after amputation, 55 CINPWT patients and 66 stump bandage patients had died (<jats:italic>P<\/jats:italic> =\u2009.82). Survival probabilities adjusted for age and gender 2\u2009years after amputation were .52 (.43\u2010.61) and .49 (.42\u2010.58), respectively, and 3\u2009years after amputation were .36 (.25\u2010.50) and .39 (.32\u2010.47), respectively. We also found no significant difference in the need for revision surgery in survival probabilities up till 3\u2009years after amputation between patients treated with CINPWT and patients treated with gauze bandage postoperatively.<\/jats:p>","DOI":"10.1111\/iwj.13176","type":"journal-article","created":{"date-parts":[[2019,8,13]],"date-time":"2019-08-13T00:59:32Z","timestamp":1565657972000},"page":"1171-1177","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Does closed incision negative wound pressure therapy in non\u2010traumatic major lower\u2010extremity amputations improve survival rates?"],"prefix":"10.1111","volume":"16","author":[{"given":"Charlotte P","family":"Stenqvist","sequence":"first","affiliation":[{"name":"Department of Orthopedic Surgery Nykoebing Falster Hospital  Nykoebing Falster Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Camilla T","family":"Nielsen","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery Nykoebing Falster Hospital  Nykoebing Falster Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"George M","family":"Napolitano","sequence":"additional","affiliation":[{"name":"Department of Public Health University of Copenhagen  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bo M","family":"Larsen","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery Nykoebing Falster Hospital  Nykoebing Falster Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mitchell J","family":"Flies","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery Nykoebing Falster Hospital  Nykoebing Falster Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ditte C","family":"Brander","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery Nykoebing Falster Hospital  Nykoebing Falster Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elsebeth","family":"Lynge","sequence":"additional","affiliation":[{"name":"Centre for Epidemiological Research, Nykoebing Falster Hospital University of Copenhagen  Nykoebing Falster Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Per","family":"Pallesen","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery Nykoebing Falster Hospital  Nykoebing Falster Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,8,12]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.5435\/JAAOS-D-17-00054"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00264-011-1321-8"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/BOT.0b013e318216b1e5"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/iwj.12612"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.10084"},{"key":"e_1_2_7_7_1","article-title":"Incisional application of negative pressure for nontraumatic lower extremity amputations: a review","volume":"34","author":"Kotha V","year":"2019","journal-title":"Surg Technol Int"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00125-017-4488-8"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2017-016030"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1093\/icvts\/ivr075"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.3109\/17453674.2016.1167524"},{"key":"e_1_2_7_12_1","article-title":"Patients in need for major lower extremity amputations are a challenge","volume":"177","author":"Wied C","year":"2015","journal-title":"Ugeskr Laeger"},{"issue":"12","key":"e_1_2_7_13_1","first-page":"A5172","article-title":"Difficult to predict early failure after major lower\u2010extremity amputations","volume":"62","author":"Kristensen MT","year":"2015","journal-title":"Dan Med J"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/dme.12320"},{"key":"e_1_2_7_15_1","unstructured":"National klinisk retningslinie for udredning og behandling af diabetiske fods\u00e5r.https:\/\/www.sst.dk\/da\/udgivelser\/2013\/~\/media\/54AAA6F78D8B4BF89929A4AFB8B68B0F.ashx. 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