{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T07:41:29Z","timestamp":1790494889202,"version":"4.1.0"},"reference-count":16,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2019,11,26]],"date-time":"2019-11-26T00:00:00Z","timestamp":1574726400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100013130","name":"Mundipharma Korea Ltd","doi-asserted-by":"publisher","award":["\u2010"],"award-info":[{"award-number":["\u2010"]}],"id":[{"id":"10.13039\/501100013130","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["International Wound Journal"],"published-print":{"date-parts":[[2020,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>This study aimed to assess the efficacy of a new povidone\u2010iodine (PVP\u2010I) foam dressing (Betafoam) vs foam dressing (Medifoam) for the management of diabetic foot ulcers. This study was conducted between March 2016 and September 2017 at 10 sites in Korea. A total of 71 patients (aged \u226519\u2009years) with type 1\/2 diabetes and early\u2010phase diabetic foot ulcers (Wagener classification grade 1\/2) were randomised to treatment with PVP\u2010I foam dressing or foam dressing for 8\u2009weeks. Wound healing, wound infection, patient satisfaction, and adverse events (AEs) were assessed. The PVP\u2010I foam and foam dressing groups were comparable in the proportion of patients with complete wound healing within 8\u2009weeks (44.4% vs 42.3%, <jats:italic>P<\/jats:italic> =\u2009.9191), mean (\u00b1SD) number of days to complete healing (31.00\u2009\u00b1\u200915.07 vs 33.27\u2009\u00b1\u200912.60\u2009days; <jats:italic>P<\/jats:italic> =\u2009.6541), and infection rates (11.1% vs 11.4%; <jats:italic>P<\/jats:italic> =\u20091.0000). Median satisfaction score (scored from 0 to 10) at the final visit was also comparable between groups (10 vs 9, <jats:italic>P<\/jats:italic> =\u2009.2889). There was no significant difference in AE incidence (27.8% vs 17.1%, <jats:italic>P<\/jats:italic> =\u2009.2836), and none of the reported AEs had a causal relationship with the dressings. The results of this study suggest that PVP\u2010I foam dressing has wound\u2010healing efficacy comparable with foam dressing, with no notable safety concerns. This study was funded by Mundipharma Korea Ltd and registered at <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"http:\/\/clinicaltrials.gov\">ClinicalTrials.gov<\/jats:ext-link> (identifier NCT02732886).<\/jats:p>","DOI":"10.1111\/iwj.13236","type":"journal-article","created":{"date-parts":[[2019,11,27]],"date-time":"2019-11-27T04:18:35Z","timestamp":1574828315000},"page":"91-99","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":34,"title":["Efficacy of a povidone\u2010iodine foam dressing (Betafoam) on diabetic foot ulcer"],"prefix":"10.1111","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1062-0580","authenticated-orcid":false,"given":"Heui C.","family":"Gwak","sequence":"first","affiliation":[{"name":"Department of Orthopedic Surgery, Busan Paik Hospital Inje University College of Medicine  Busan South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seung H.","family":"Han","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Gangnam Severance Hospital Yonsei University College of Medicine  Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinwoo","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Severance Hospital Yonsei University College of Medicine  Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sejin","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery, KangBuk Samsung Hospital SungKyunKwan University School of Medicine  Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ki\u2010Sun","family":"Sung","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery, Samsung Medical Center Sungkyunkwan University School of Medicine  Seoul South 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Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyunghee","family":"Kwak","sequence":"additional","affiliation":[{"name":"Department of Medical Affairs Mundipharma Korea Ltd  Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyung\u2010Jin","family":"Chung","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics Inje University Sanggye Paik Hospital  Seoul South 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