{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,5]],"date-time":"2026-02-05T09:04:18Z","timestamp":1770282258632,"version":"3.49.0"},"reference-count":14,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2019,12,19]],"date-time":"2019-12-19T00:00:00Z","timestamp":1576713600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["International Wound Journal"],"published-print":{"date-parts":[[2020,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Tissue adhesives have gained increasing use as a possible method of wound closure. We compared the use of 2\u2010octyl cyanoacrylate (OCA) or subcuticular suture in incisions sutures for the closure of laparoscopic cholecystectomy port incisions. A prospective randomised controlled trial was performed. Patients were randomised to have closure of laparoscopic port sites using either OCA or sutures. Patients were reviewed at 24\u2009hours and returned for follow\u2010up 1 week and 1\u2009month after postoperatively. At these times, different wound characteristics were documented: Two tools were used to measure the cosmetic result using Hollander wound evaluation scale (HWES) and the patient and observer scar assessment scale (POSAS). A total of 70 patients, 35 in each group were enrolled. The wounds were closed significantly faster in the OCA group (mean 229.16 [\u00b143.7] seconds versus 258.82 [\u00b151.7] seconds, <jats:italic>P<\/jats:italic> =\u2009.01). Statistically significant difference in favour of using OCA was found for dehiscence (17.1% versus none in the suture group, <jats:italic>P<\/jats:italic> =\u2009.025) after 1 week. However, no difference was found for wound dehiscence after 1 month. OCA and suture groups did not differ significantly on patient satisfaction. There were no differences in the percentage of wounds achieving optimal scores on the HWES (suture 85.7% versus OCA 74.2%, <jats:italic>P<\/jats:italic> =\u2009.169). Nerveless, wound evolution was judged to be significantly better in the OCA group using POSAS. Patients' median POSAS was 9.45 (6\u201311) and 11.43 (10\u201313) in the OCA and suture groups, respectively (<jats:italic>P<\/jats:italic> =\u2009.005), and surgeon's median POSAS was 9.42 (6\u201311) and 11.48 (10\u201313) in the OCA and suture groups, respectively (<jats:italic>P<\/jats:italic> =\u2009.006). N\u2010butyl\u2010cyanoacrylate tissue adhesive is an acceptable technique for the closure of laparoscopic wounds with less operative time, and cosmetic results are comparable to suturing.<\/jats:p>","DOI":"10.1111\/iwj.13294","type":"journal-article","created":{"date-parts":[[2019,12,19]],"date-time":"2019-12-19T08:42:26Z","timestamp":1576744946000},"page":"449-454","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["A randomised clinical trial to compare octyl cyanoacrylate with absorbable monofilament sutures for the closure of laparoscopic cholecystectomy port incisions"],"prefix":"10.1111","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7578-4071","authenticated-orcid":false,"given":"Yacine","family":"Ben Safta","sequence":"first","affiliation":[{"name":"A21 Surgery Department Charles Nicolle Hospital, Faculty of medicine of Tunis\/Tunis El Manar University  Tunis Tunisia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohamed","family":"Maatouk","sequence":"additional","affiliation":[{"name":"A21 Surgery Department Charles Nicolle Hospital, Faculty of medicine of Tunis\/Tunis El Manar University  Tunis Tunisia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohamed T.","family":"Bouzidi","sequence":"additional","affiliation":[{"name":"A21 Surgery Department Charles Nicolle Hospital, Faculty of medicine of Tunis\/Tunis El Manar University  Tunis Tunisia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nabil","family":"Sakly","sequence":"additional","affiliation":[{"name":"Faculty of Pharmacy of Monastir, Biology Clinique B Department"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aymen","family":"Mabrouk","sequence":"additional","affiliation":[{"name":"A21 Surgery Department Charles Nicolle Hospital, Faculty of medicine of Tunis\/Tunis El Manar University  Tunis 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El Manar University  Tunis Tunisia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mounir","family":"Ben Moussa","sequence":"additional","affiliation":[{"name":"A21 Surgery Department Charles Nicolle Hospital, Faculty of medicine of Tunis\/Tunis El Manar University  Tunis Tunisia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,12,19]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/00129689-200606000-00005"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1089\/089277903772036235"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1089\/lap.2004.14.209"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1072-7515(03)00119-4"},{"key":"e_1_2_5_6_1","volume-title":"L'essai th\u00e9rapeutique chez l'homme","author":"Schwartz 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