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Its use has many advantages over standard wound care, as it contains pluripotent cells, nutrients, anti\u2010fibrotic and anti\u2010inflammatory cytokines, growth factors and extracellular matrix (ECM) proteins. Placental tissues can be prepared as a medical component, an advanced therapy medicinal product or a tissue graft. In addition to basic preparation procedures such as washing, rinsing, cutting, drying and sterilisation, there are many optional steps such as perforation, crosslinking and decellularisation. Finally, transplants should be properly stored\u2014in cryopreserved or dehydrated form. In recent years, many studies including basic science and clinical trials have proven the potential to expand the use of amniotic membrane and amnion\u2010derived cells to the fields of orthopaedics, dentistry, surgery, urology, vascular tissue engineering and even oncology. In this review, we discuss the role of placental tissues in skin wound healing and in the treatment of various diseases, with particular emphasis on bullous diseases. We also describe some patented procedures for placental tissue grafts preparation.<\/jats:p>","DOI":"10.1111\/iwj.13305","type":"journal-article","created":{"date-parts":[[2020,1,15]],"date-time":"2020-01-15T12:47:26Z","timestamp":1579092446000},"page":"491-507","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["Preparation of placental tissue transplants and their application in skin wound healing and chosen skin bullous diseases \u2010 Stevens\u2010Johnson syndrome and toxic epidermal necrolysis treatment"],"prefix":"10.1111","volume":"17","author":[{"given":"Agnieszka","family":"Klama\u2010Bary\u0142a","sequence":"first","affiliation":[{"name":"The Burn Centre of Stanis\u0142aw Sakiel in Siemianowice \u015al\u0105skie  Siemianowice \u015al\u0105skie 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