{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,26]],"date-time":"2026-07-26T05:55:49Z","timestamp":1785045349272,"version":"3.55.0"},"reference-count":21,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2020,3,20]],"date-time":"2020-03-20T00:00:00Z","timestamp":1584662400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["International Wound Journal"],"published-print":{"date-parts":[[2020,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Identifying risk factors for mortality is crucial in the management of diabetic foot syndrome. We aimed to evaluate risk factors for mortality in patients with diabetic foot infection (DFI). A retrospective chart review was conducted on 401 patients from 2010 through 2019. Our primary endpoint was in\u2010hospital mortality. Patients were divided into two groups according to the outcome (survival or death). Clinical data were compared between the two groups statistically. A total of 401 patients were enrolled in the study, 280 (69.8%) of them were male and the mean age was 59.6\u2009\u00b1\u200911.1\u2009years. The mean follow\u2010up period was 23.7\u2009\u00b1\u200922.9 months. In\u2010hospital mortality rate was 3%. Univariate analysis indicated that ischaemic wound (<jats:italic>P<\/jats:italic> = .023), hindfoot infection (<jats:italic>P<\/jats:italic> = .038), whole foot infection (<jats:italic>P<\/jats:italic> = .010), peripheral arterial disease (<jats:italic>P<\/jats:italic> = .024), high leucocyte levels (&gt;12\u2009040\u2009K\/\u03bcL) (<jats:italic>P<\/jats:italic> = .001), high thrombocyte levels (&gt;378\u2009000\u2009K\/\u03bcL) (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001), high C\u2010reactive protein levels (&gt;8.81\u2009mg\/dL) (<jats:italic>P<\/jats:italic> = .022), and polymicrobial growth in deep tissue culture (<jats:italic>P<\/jats:italic> = .041) were significant parameters in predicting mortality. In multivariate analysis, peripheral arterial disease (odds ratio [OR]: 13.430, 95% confidence interval [Cl]: 1.129\u201059.692; <jats:italic>P<\/jats:italic> = .040), high thrombocyte levels (OR: 1.000, 95% Cl: 1.000\u20101.000; <jats:italic>P<\/jats:italic> = .022), and polymicrobial growth in deep tissue culture (OR: 7.790, 95% Cl: 1.592\u201038.118; <jats:italic>P<\/jats:italic> = .011) were independent risk factors for mortality. In conclusion, peripheral arterial disease, high thrombocyte levels, and polymicrobial growth in deep tissue culture were independent risk factors for mortality in DFI.<\/jats:p>","DOI":"10.1111\/iwj.13343","type":"journal-article","created":{"date-parts":[[2020,3,20]],"date-time":"2020-03-20T18:20:35Z","timestamp":1584728435000},"page":"880-889","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["Evaluation of mortality risk factors in diabetic foot infections"],"prefix":"10.1111","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1365-3329","authenticated-orcid":false,"given":"Pinar","family":"Sen","sequence":"first","affiliation":[{"name":"Department of Infectious Diseases and Clinical Microbiology Izmir Katip Celebi University Ataturk Training and Research Hospital  Izmir Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tuna","family":"Demirdal","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases and Clinical Microbiology Izmir Katip Celebi University Ataturk Training and Research Hospital  Izmir Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,3,20]]},"reference":[{"issue":"19","key":"e_1_2_7_2_1","first-page":"30123","article-title":"Five\u2010year mortality in patients with diabetic foot ulcer during 2009\u20132010 was lower than expected","volume":"1262","author":"Amadou C","year":"2019","journal-title":"Diabetes Metab"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc09-0651"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/ijcp.13006"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdiacomp.2016.11.020"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11883-017-0680-z"},{"key":"e_1_2_7_7_1","first-page":"CD009061","article-title":"Systemic antibiotics for treating diabetic foot infections","volume":"9","author":"Selva Olid A","year":"2015","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jiac.2015.12.007"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cis346"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.diabres.2018.08.009"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.4239\/wjd.v6.i3.489"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00125-015-3785-3"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.3402\/dfa.v4i0.21288"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc08-1242"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-019-46961-8"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc13-1212"},{"issue":"4","key":"e_1_2_7_17_1","first-page":"288","article-title":"Infection of foot ulcers with Staphylococcus aureus associated with increased mortality in diabetic patients","volume":"3","author":"Mantey I","year":"2000","journal-title":"Commun Dis Public Health"},{"issue":"1","key":"e_1_2_7_18_1","first-page":"3","article-title":"Procalcitonin as a diagnostic and prognostic marker in diabetic foot infection. A current literature review","volume":"56","author":"Velissaris D","year":"2018","journal-title":"Rom J Intern Med"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1155\/2019\/4312737"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.krcp.2013.10.001"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.diabet.2010.10.003"},{"issue":"2","key":"e_1_2_7_22_1","first-page":"26","article-title":"Diabetic foot infections: a comprehensive overview","volume":"23","author":"Pitocco D","year":"2019","journal-title":"Eur Rev Med Pharmacol Sci"}],"container-title":["International Wound Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fiwj.13343","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/iwj.13343","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/iwj.13343","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/iwj.13343","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,3]],"date-time":"2023-09-03T01:26:04Z","timestamp":1693704364000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/iwj.13343"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,3,20]]},"references-count":21,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2020,8]]}},"alternative-id":["10.1111\/iwj.13343"],"URL":"https:\/\/doi.org\/10.1111\/iwj.13343","archive":["Portico"],"relation":{},"ISSN":["1742-4801","1742-481X"],"issn-type":[{"value":"1742-4801","type":"print"},{"value":"1742-481X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,3,20]]},"assertion":[{"value":"2020-02-13","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-03-09","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-03-20","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}