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Early identification of patients at risk of developing ICLUs may represent the best form of prevention and appropriate management. In this study, we used a Prediction System for Chronic Leg Ulcers (PredyCLU) based on fuzzy logic applied to patients with PAD. The patient population consisted of 80 patients with PAD, of which 40 patients (30 males [75%] and 10 females [25%]; mean age 66.18\u2009years; median age 67.50\u2009years) had ICLUs and represented the case group. Forty patients (100%) (27 males [67.50%] and 13 females [32.50%]; mean age 66.43\u2009years; median age 66.50\u2009years) did not have ICLUs and represented the control group. In patients of the case group, the higher was the risk calculated with the PredyCLU the more severe were the clinical manifestations recorded. In this study, the PredyCLU algorithm was retrospectively applied on a multicentre population of 80 patients with PAD. The PredyCLU algorithm provided a reliable risk score for the risk of ICLUs in patients with PAD.<\/jats:p>","DOI":"10.1111\/iwj.13360","type":"journal-article","created":{"date-parts":[[2020,4,14]],"date-time":"2020-04-14T03:39:51Z","timestamp":1586835591000},"page":"987-991","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["<scp>PredyCLU<\/scp>: A prediction system for chronic leg ulcers based on fuzzy logic; part <scp>II<\/scp>\u2014Exploring the arterial side"],"prefix":"10.1111","volume":"17","author":[{"given":"Raffaele","family":"Serra","sequence":"first","affiliation":[{"name":"Interuniversity Center of Phlebolymphology (CIFL) International Research and Educational Program in Clinical and Experimental Biotechnology\u201d  Catanzaro Italy"},{"name":"Department of Medical and Surgical Sciences University of Catanzaro  Catanzaro Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Umberto M.","family":"Bracale","sequence":"additional","affiliation":[{"name":"Department of Public Health University of Naples \u201cFederico II\u201d  Naples Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Barbetta","sequence":"additional","affiliation":[{"name":"Department of Medical and Surgical Sciences University of Catanzaro  Catanzaro Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicola","family":"Ielapi","sequence":"additional","affiliation":[{"name":"Interuniversity Center of Phlebolymphology (CIFL) International Research and Educational Program in Clinical and Experimental Biotechnology\u201d  Catanzaro Italy"},{"name":"Department of Medical and Surgical Sciences University of Catanzaro  Catanzaro Italy"},{"name":"Department of Public Health and Infectious Diseases Sapienza University of Rome  Rome Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Noemi","family":"Licastro","sequence":"additional","affiliation":[{"name":"Interuniversity Center of Phlebolymphology (CIFL) International Research and Educational Program in Clinical and Experimental Biotechnology\u201d  Catanzaro Italy"},{"name":"Department of Medical and Surgical Sciences University of Catanzaro  Catanzaro Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessandro","family":"Gallo","sequence":"additional","affiliation":[{"name":"Interuniversity Center of Phlebolymphology (CIFL) International Research and Educational Program in Clinical and Experimental Biotechnology\u201d  Catanzaro Italy"},{"name":"Department of Medical and Surgical Sciences University of Catanzaro  Catanzaro Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Salvatore","family":"Fregola","sequence":"additional","affiliation":[{"name":"Interuniversity Center of Phlebolymphology (CIFL) International Research and Educational Program in Clinical and Experimental Biotechnology\u201d  Catanzaro Italy"},{"name":"Department of Medical and Surgical Sciences University of Catanzaro  Catanzaro Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Davide","family":"Turchino","sequence":"additional","affiliation":[{"name":"Department of Public Health University of Naples \u201cFederico II\u201d  Naples Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vincenzo","family":"Gasbarro","sequence":"additional","affiliation":[{"name":"Interuniversity Center of Phlebolymphology (CIFL) International Research and Educational Program in Clinical and Experimental Biotechnology\u201d  Catanzaro Italy"},{"name":"Department of Morphology, Surgery and Experimental Medicine University of Ferrara  Ferrara Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pasquale","family":"Mastroroberto","sequence":"additional","affiliation":[{"name":"Department of Experimental and Clinical Medicine University of Catanzaro  Catanzaro Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefano","family":"de Franciscis","sequence":"additional","affiliation":[{"name":"Interuniversity Center of Phlebolymphology (CIFL) International Research and Educational Program in Clinical and Experimental Biotechnology\u201d  Catanzaro Italy"},{"name":"Department of Medical and Surgical Sciences University of Catanzaro  Catanzaro Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,4,13]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejim.2008.09.013"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.atherosclerosis.2004.03.009"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.105.608679"},{"issue":"1","key":"e_1_2_6_5_1","first-page":"S1","article-title":"Management of peripheral arterial disease (PAD). 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