{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T00:53:05Z","timestamp":1787014385536,"version":"build-2736575974"},"reference-count":25,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2020,7,9]],"date-time":"2020-07-09T00:00:00Z","timestamp":1594252800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["International Wound Journal"],"published-print":{"date-parts":[[2020,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Wound\u2010healing disorders are common complications in bilateral reduction mammaplasty. Traditional electrosurgical devices generate large amounts of thermal energy, often causing extensive thermal\u2010related collateral tissue damage. This study aimed to retrospectively analyse the operative performance of a novel low\u2010thermal plasma dissection device (pulsed electron avalanche knife\u2014PEAK PlasmaBlade\u2122) compared with traditional electrosurgery. Twenty patients with breast hypertrophy were randomly treated with PEAK PlasmaBlade\u2122 on one breast and conventional electrosurgery on the other. Primary outcome measures were resection weight, drain duration, total drainage volume, and drain output on the first postoperative day. Breasts treated with PEAK PlasmaBlade\u2122 had significantly higher resection weights (728.0 \u00b1\u2009460.1 g vs 661.6 \u00b1\u2009463.4 g;\n                    <jats:italic>P<\/jats:italic>\n                    =\u2009.038), significantly lower drain output on the first postoperative day (15.9 \u00b1\u200915.2 mL vs 27.6 \u00b1\u200923.5 mL;\n                    <jats:italic>P<\/jats:italic>\n                    =\u2009.023), and significantly lower drain durations (2.8 \u00b1\u20091.0\u2009days vs 3.3 \u00b1\u20091.0\u2009days;\n                    <jats:italic>P<\/jats:italic>\n                    =\u2009.030). Mean total drainage volume was lower where breast reduction was performed with PEAK PlasmaBlade\u2122, but this difference was not significant. No major complications occurred, but wound\u2010healing disorders were documented in almost one\u2010third of the patients (35.0%, n = 7). The PEAK PlasmaBlade\u2122 seems to be superior to conventional electrosurgery for bilateral reduction mammaplasty in terms of tissue damage and wound healing.\n                  <\/jats:p>","DOI":"10.1111\/iwj.13452","type":"journal-article","created":{"date-parts":[[2020,7,9]],"date-time":"2020-07-09T08:36:39Z","timestamp":1594283799000},"page":"1695-1701","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Bilateral reduction mammaplasty with pulsed electron avalanche knife\n                    <scp>PlasmaBlade<\/scp>\n                    \u2122 and conventional electrosurgical surgery: A retrospective, randomised controlled clinical trial"],"prefix":"10.1111","volume":"17","author":[{"given":"Torsten","family":"Schlosshauer","sequence":"first","affiliation":[{"name":"Department of Plastic, Aesthetic, Reconstructive and Hand Surgery AGAPLESION Evangelical Hospital Central State of Hesse  Giessen Germany"},{"name":"Department of Plastic and Aesthetic, Reconstructive and Hand Surgery AGAPLESION Markus Hospital  Frankfurt am Main Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcus","family":"Kiehlmann","sequence":"additional","affiliation":[{"name":"Department of Plastic and Aesthetic, Reconstructive and Hand Surgery AGAPLESION Markus Hospital  Frankfurt am Main Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jens","family":"Rothenberger","sequence":"additional","affiliation":[{"name":"Department of Plastic and Aesthetic, Reconstructive and Hand Surgery AGAPLESION Markus Hospital  Frankfurt am Main Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Sader","sequence":"additional","affiliation":[{"name":"Department for Oral, Cranio\u2010Maxillofacial and Facial Plastic Surgery Medical Center of the Goethe University Frankfurt  Frankfurt Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ulrich M.","family":"Rieger","sequence":"additional","affiliation":[{"name":"Department of Plastic and Aesthetic, Reconstructive and Hand Surgery AGAPLESION Markus Hospital  Frankfurt am Main Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,7,9]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0b013e318262f0c0"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00586-019-06155-2"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/GOX.0000000000002324"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0b013e31824129ee"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1080\/0167482X.2016.1270936"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.prs.0000304238.43482.9c"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0b013e3182a014f6"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2016.11.028"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/SAP.0000000000001804"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0167746"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0b013e3181bcee87"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0b013e31821741ed"},{"key":"e_1_2_7_14_1","first-page":"1278","article-title":"Chen the PEAK plasma blade may reduce postoperative analgesic medication use in breast cancer surgery","volume":"1","author":"Huang C\u2010Y","year":"2016","journal-title":"Clin Surg"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.4174\/astr.2018.95.3.129"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/GOX.0000000000002035"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0036-1583414"},{"key":"e_1_2_7_18_1","unstructured":"Medtronic Surgical Technologies. PEAK PlasmaBlade 4.0 in Bilateral Breast Reduction (PRECISE). NCT00986453. 01\/01\/2013.https:\/\/clinicaltrials.gov\/ct2\/show\/record\/NCT00986453#wrapper. Accessed March 30 2020."},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-197701000-00011"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjoto.2019.03.011"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1177\/014556131709600718"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2016.07.007"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.24830"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1093\/asj\/sjy177"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/pace.12488"},{"key":"e_1_2_7_26_1","volume-title":"Pulsed Electron Avalanche Knife (PEAK) PlasmaBlade versus Traditional Electrocautery for Surgery: A Review of Clinical Effectiveness and Cost\u2010Effectiveness","author":"Peprah K","year":"2019"}],"container-title":["International Wound Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fiwj.13452","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/iwj.13452","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/iwj.13452","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/iwj.13452","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,27]],"date-time":"2025-05-27T09:36:15Z","timestamp":1748338575000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/iwj.13452"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,7,9]]},"references-count":25,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2020,12]]}},"alternative-id":["10.1111\/iwj.13452"],"URL":"https:\/\/doi.org\/10.1111\/iwj.13452","archive":["Portico"],"relation":{},"ISSN":["1742-4801","1742-481X"],"issn-type":[{"value":"1742-4801","type":"print"},{"value":"1742-481X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,7,9]]},"assertion":[{"value":"2020-04-23","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-06-22","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-07-09","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}