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Negative pressure wound therapy (NPWT) has long been used for treatment of soft tissue injury or defects. NPWT may reduce the incident of SSI following spinal fusion procedures; however, its potential applications need further clarification. Thus, we conducted a retrospective analysis of two cohorts to compare NPWT to traditional sterile dressings following spinal fusions in regards to post\u2010operative outcomes. Following institutional review board approval, 42 patients who had a NPWT were matched by type of surgery to 42 patients who had traditional dressings. A retrospective chart\u2010review was completed. Outcome measures, particularly SSI and need for reoperation, were analyzed using one\u2010way ANOVA for both univariate and multivariate analysis. When controlled for sex and body\u2010mass index, the use of a NPWT was independently correlated with decreased SSI (<jats:italic>P<\/jats:italic> = .035). Superficial dehiscence, seroma, need for additional outpatient care, and need for operative revision were all found to occur at higher rates in the traditional dressing cohort. Closed incisional negative pressure wound therapy provides a cost\u2010effective method of decreasing surgical site infection for posterior elective spine surgeries.<\/jats:p>","DOI":"10.1111\/iwj.13507","type":"journal-article","created":{"date-parts":[[2020,11,25]],"date-time":"2020-11-25T15:22:28Z","timestamp":1606317748000},"page":"158-163","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":29,"title":["Negative pressure wound therapy in spinal fusion patients"],"prefix":"10.1111","volume":"18","author":[{"given":"Asad S.","family":"Akhter","sequence":"first","affiliation":[{"name":"Department of Neurosurgery The Ohio State University Wexner Medical Center  Columbus Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin G.","family":"McGahan","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery The Ohio State University Wexner Medical Center  Columbus Ohio 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