{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T07:27:08Z","timestamp":1790321228432,"version":"4.1.0"},"reference-count":31,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2020,11,25]],"date-time":"2020-11-25T00:00:00Z","timestamp":1606262400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["International Wound Journal"],"published-print":{"date-parts":[[2021,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Activation of the venous muscle pumps by neuromuscular stimulation of the common peroneal nerve has been previously shown to increase venous and arterial flow in the legs of healthy subjects. The aim of this study is to determine whether a similar effect is observed in patients with chronic venous leg ulcers. 1\u2009Hz intermittent electrostimulation of the common peroneal nerve was applied to 14 patients with ulcers between 1 and 10\u2009cm in diameter, eliciting a small, painless, regular, muscular twitch of the leg. Flow was measured using Duplex ultrasound in the popliteal vein and the popliteal artery. Peak arterial velocity increased from 57 to 78\u2009cm\/s (<jats:italic>P<\/jats:italic> =\u2009.001) in sitting position, and from 79 to 98\u2009cm\/s in recumbent position (<jats:italic>P<\/jats:italic> =\u2009.001). Peak venous velocity increased from 10 to 33\u2009cm\/s (<jats:italic>P<\/jats:italic> =\u2009.001) sitting, and from 14 to 47\u2009cm\/s (<jats:italic>P<\/jats:italic> =\u2009.001) recumbent. Significant increases were observed in both venous and arterial blood flow in the lower limb. This suggestsed that activation of the venous muscle pump and improvement of arterial flow assisted oxygen delivery at the wound site. Moreover this may be a worthwhile intervention to assist in the healing of venous leg ulcers, and may provide a mechanistic explanation for the increased healing rates previously reported with neuromuscular stimulation of the common peroneal nerve.<\/jats:p>","DOI":"10.1111\/iwj.13510","type":"journal-article","created":{"date-parts":[[2020,11,25]],"date-time":"2020-11-25T15:22:47Z","timestamp":1606317767000},"page":"187-193","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Neuromuscular stimulation of the common peroneal nerve increases arterial and venous velocity in patients with venous leg ulcers"],"prefix":"10.1111","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3228-1225","authenticated-orcid":false,"given":"Saroj K.","family":"Das","sequence":"first","affiliation":[{"name":"Consultant Vascular &amp; Endovascular Surgeon, West London Vascular and Intervention Centre (WeLVIC) London North West Health Care NHS Trust  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luxmi","family":"Dhoonmoon","sequence":"additional","affiliation":[{"name":"Central and North West Health Care NHS Trust  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Swati","family":"Chhabra","sequence":"additional","affiliation":[{"name":"London North West University Health care NHS Trust  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,11,25]]},"reference":[{"issue":"8","key":"e_1_2_9_2_1","first-page":"989","article-title":"Diagnosis and treatment of venous ulcers","volume":"81","author":"Collins L","year":"2010","journal-title":"Am Fam Physician"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.332.7537.347"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/0741-5214(94)90223-2"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/WON.0000000000000242"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0031-1278361"},{"issue":"2","key":"e_1_2_9_7_1","first-page":"158","article-title":"Microcirculation in the foot is augmented by neuromuscular stimulation via the common peroneal nerve in different lower limb postures: a potential treatment for leg ulcers","volume":"34","author":"Warwick DJ","year":"2015","journal-title":"Int Angiol"},{"key":"e_1_2_9_8_1","unstructured":"WilliamsKJ.Chapter 7.1. 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