{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,20]],"date-time":"2026-04-20T19:15:23Z","timestamp":1776712523188,"version":"3.51.2"},"reference-count":19,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2020,10,30]],"date-time":"2020-10-30T00:00:00Z","timestamp":1604016000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["International Wound Journal"],"published-print":{"date-parts":[[2021,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The purpose of this study was to evaluate the therapeutic effects of artificial dermis combined with autologous split\u2010thickness skin grafting (STSG) compared with autologous intermediate\u2010thickness skin grafting (ITSG) alone in severely burned patients. Fifty\u2010six severely burned patients admitted to our hospital from December 2017 to January 2019 were enrolled and evenly grouped according to the random number table method [AD\u2010STSG group: 28 patients, receiving the treatment of artificial dermis (AD) combined with autologous STSG; ITSG group: 28 patients, receiving autologous ITSG treatment alone]. The healing time and Vancouver Scar Scale (VSS) score of the donor area and graft area, survival rate and infection status of the autologous skin, psychological status (determined by Self\u2010rating Anxiety Scale and Self\u2010rating Depression Scale), and the activity of functional parts of all enrolled patients were included in the evaluation. General items of patients in AD\u2010STSG group and ITSG group, including age, sex, and degree of burn, were all comparable. A significantly shortened healing time of donor skin in AD\u2010STSG group was observed when compared with ITSG group (<jats:italic>P<\/jats:italic>\u2009&lt;\u2009.05) while the recipient skin healed in the same tendency between the two groups. In addition, 21\u2009days after the operation, AD\u2010STSG group presented with significantly higher survival rate of graft skin than ITSG group (<jats:italic>P<\/jats:italic>\u2009&lt;\u2009.05) while same infection status was observed in the two groups. Significantly lower VSS scores were found in AD\u2010STSG group than that in ITSG group 3\u2010, 6\u2010 and 10\u2010months after operation (<jats:italic>P<\/jats:italic>\u2009&lt;\u2009.05). Statistical difference regarding psychological status of patients from two groups was unobservable before operation while significantly lower Self\u2010rating Anxiety Scale (SAS) and Self\u2010rating Depression Scale (SDS) scores were found in AD\u2010STSG group than that in ITSG group 3\u2010, 6\u2010 and 10\u2010months after operation (<jats:italic>P<\/jats:italic>\u2009&lt;\u2009.05). Also, AD\u2010STSG group presented improved mobility of functional part than that in ITSG group 10\u2010months after operation without statistical difference (<jats:italic>P<\/jats:italic> = .051). Artificial dermis combined with autologous split\u2010thickness skin grafting showed better therapeutic outcomes for the treatment of severely burned patients than autologous intermediate\u2010thickness skin grafting in terms of graft healing time, scar formation, psychological recovery, and perhaps in functional reconstruction.<\/jats:p>","DOI":"10.1111\/iwj.13518","type":"journal-article","created":{"date-parts":[[2020,10,30]],"date-time":"2020-10-30T08:38:08Z","timestamp":1604047088000},"page":"24-31","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["RETRACTED: Comparison of therapeutic effects between artificial dermis combined with autologous split\u2010thickness skin grafting and autologous intermediate\u2010thickness skin grafting alone in severely burned patients: A prospective randomised study"],"prefix":"10.1111","volume":"18","author":[{"given":"Feng","family":"Shang","sequence":"first","affiliation":[{"name":"Department of Burns The Second Affiliated Hospital of Shandong First Medical University  Tai'an Shandong China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yan\u2010Hua","family":"Lu","sequence":"additional","affiliation":[{"name":"Department of Burns The Second Affiliated Hospital of Shandong First Medical University  Tai'an Shandong China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jian","family":"Gao","sequence":"additional","affiliation":[{"name":"Department of General Surgery, The First People's Hospital of Tai'an Shandong First Medical University  Tai'an Shandong China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9906-9539","authenticated-orcid":false,"given":"Qiang","family":"Hou","sequence":"additional","affiliation":[{"name":"Department of Burns The Second Affiliated Hospital of Shandong First Medical University  Tai'an Shandong China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,10,30]]},"reference":[{"issue":"10","key":"e_1_2_7_2_1","first-page":"1092","article-title":"R\u00e9habilitation du br\u00fbl\u00e9 grave [severe burned patient rehabilitation]","volume":"68","author":"Nicolas C","year":"2018","journal-title":"Rev Prat"},{"issue":"8","key":"e_1_2_7_3_1","first-page":"608","article-title":"Clinical effects of artificial dermis combined with vacuum sealing drainage and autologous split\u2010thickness skin graft in repair of scar contracture deformity after extensive burn","volume":"35","author":"Chen S","year":"2019","journal-title":"Zhonghua Shao Shang Za Zhi"},{"issue":"017","key":"e_1_2_7_4_1","first-page":"56","article-title":"Nursing practice of Decellularized dermal matrix dressing in treating deep II level burn wound of children with major burn","volume":"34","author":"Luo XL","year":"2017","journal-title":"Nurs J Chin People Liber Army"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/ans.13920"},{"issue":"5","key":"e_1_2_7_6_1","first-page":"360","article-title":"Comparative study on repair of full\u2010thickness burn wound with different artificial dermal stent in pigs","volume":"26","author":"Xu SJ","year":"2010","journal-title":"Zhonghua Zheng Xing Wai Ke Za Zhi"},{"issue":"001","key":"e_1_2_7_7_1","first-page":"34","article-title":"Evaluate the clinical effectiveness of domestic double layer artificial dermis dressing with autologous split\u2010thickness skin for treatment of wounds with bone or tendon exposure","volume":"011","author":"Gong C","year":"2016","journal-title":"Chin J Injur Repair Wound Heal"},{"issue":"3","key":"e_1_2_7_8_1","first-page":"240","article-title":"Reliability of Vancouver scar scale","volume":"21","author":"Liu HB","year":"2006","journal-title":"Chin J Rehabilitat Med"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.janxdis.2005.08.002"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.1965.01730060026004"},{"issue":"4","key":"e_1_2_7_11_1","first-page":"204","article-title":"A preliminary study on correction of scar contracture of joints with minced skin autograft after severe extensive burn. 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