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Only studies on reconstructing plantar defects with perforator flaps were included, and specific data were required for each patient in the included studies. A total of 14 studies involving 111 flaps were identified and included in the meta\u2010analysis. Our meta\u2010analysis identified two risk factors for postoperative complications: flap size over 50\u2009cm<jats:sup>2<\/jats:sup> (risk ratio [RR]\u00a0=\u00a03.12; <jats:italic>P<\/jats:italic>\u00a0=\u00a0.02), diabetes mellitus foot (RR\u00a0=\u00a03.26; <jats:italic>P<\/jats:italic>\u00a0=\u00a0.03). No significant differences were found regarding heel defects (<jats:italic>P<\/jats:italic>\u00a0=\u00a0.34), single perforator (<jats:italic>P<\/jats:italic>\u00a0=\u00a0.57), age older than 60\u2009years (<jats:italic>P<\/jats:italic>\u00a0=\u00a0.19), chronic aetiology (<jats:italic>P<\/jats:italic>\u00a0=\u00a0.13), trauma (<jats:italic>P<\/jats:italic>\u00a0=\u00a0.33), tumour resection (<jats:italic>P<\/jats:italic>\u00a0=\u00a0.60), ulcer (<jats:italic>P<\/jats:italic>\u00a0=\u00a0.84), and burn (<jats:italic>P<\/jats:italic>\u00a0=\u00a0.76). Although more high\u2010quality studies with adequate sample sizes are needed, this meta\u2010analysis indicated that flap size over 50\u2009cm<jats:sup>2<\/jats:sup> and diabetes mellitus foot were significant risk factors for postoperative complications of perforator flaps in plantar reconstruction.<\/jats:p>","DOI":"10.1111\/iwj.13552","type":"journal-article","created":{"date-parts":[[2021,3,6]],"date-time":"2021-03-06T08:01:39Z","timestamp":1615017699000},"page":"525-535","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["A systematic review and <scp>meta\u2010analysis<\/scp> of perforator flaps in plantar defects: Risk analysis of complications"],"prefix":"10.1111","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4032-0768","authenticated-orcid":false,"given":"Wei","family":"Zhang","sequence":"first","affiliation":[{"name":"Department of Plastic Surgery The First Affiliated Hospital of Anhui 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