{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T12:11:39Z","timestamp":1787314299715,"version":"build-2736575974"},"reference-count":45,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2021,5,7]],"date-time":"2021-05-07T00:00:00Z","timestamp":1620345600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["International Wound Journal"],"published-print":{"date-parts":[[2021,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Skin cleansers and protectants protect skin from incontinent matter to reduce the risk of incontinence\u2010associated dermatitis (IAD), but their effectiveness treating established IAD in the tropics is unknown. We conducted an open\u2010label cluster randomised trial to compare the effectiveness of a combined regimen of (1) specialised skin cleansers with disposable body wipes and (2) either an acrylic terpolymer (T1) or zinc oxide (T2) skin protectant against disposable body wipes and zinc oxide protectant (control) in promoting IAD healing and reducing the risk of deterioration. Eighty\u2010four patients were recruited in a tertiary hospital in Singapore between April 2019 and January 2020 (T1: n\u00a0=\u00a023; T2: n\u00a0=\u00a037; Control: n\u00a0=\u00a024). Although not statistically significant, patients treated with T1 and T2 were 1.5 times as likely to experience IAD healing within seven\u2009days compared with the control (\n                    <jats:italic>P<\/jats:italic>\n                    \u00a0=\u00a0.66). Healing was more pronounced in participants with skin loss treated with T1 or T2. No treatment was superior in preventing IAD deterioration, the prevalence of which remained small (8%\u201014%). While skin cleaning and protectants reduced the overall risk of skin deterioration, the addition of skin cleansers enhanced IAD healing within a short period, an important consideration for future research examining IAD treatment in acute care.\n                  <\/jats:p>","DOI":"10.1111\/iwj.13588","type":"journal-article","created":{"date-parts":[[2021,5,8]],"date-time":"2021-05-08T18:02:38Z","timestamp":1620496958000},"page":"862-873","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":32,"title":["Effectiveness of skin cleanser and protectant regimen on incontinence\u2010associated dermatitis outcomes in acute care patients: A cluster randomised trial"],"prefix":"10.1111","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0667-3954","authenticated-orcid":false,"suffix":"Jr","given":"George Frederick","family":"Glass","sequence":"first","affiliation":[{"name":"Nursing Research Unit, Tan Tock Seng Hospital  Singapore Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cheng Cheng Karine","family":"Goh","sequence":"additional","affiliation":[{"name":"Nursing Service, Tan Tock Seng Hospital  Singapore Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Run Qi","family":"Cheong","sequence":"additional","affiliation":[{"name":"Nursing Research Unit, Tan Tock Seng Hospital  Singapore Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhi Lei","family":"Ong","sequence":"additional","affiliation":[{"name":"Nursing Research Unit, Tan Tock Seng Hospital  Singapore Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6679-8324","authenticated-orcid":false,"given":"Peck Chui Betty","family":"Khong","sequence":"additional","affiliation":[{"name":"Nursing Service, Tan Tock Seng Hospital  Singapore Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8662-4487","authenticated-orcid":false,"given":"Ee\u2010Yuee","family":"Chan","sequence":"additional","affiliation":[{"name":"Nursing Research Unit, Tan Tock Seng Hospital  Singapore Singapore"},{"name":"Alice Lee Centre of Nursing Studies National University of Singapore  Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,5,7]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40266-017-0507-1"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/XEB.0000000000000067"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.WON.0000270820.91694.1f"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/iwj.12699"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.12968\/bjon.2017.26.20.1128"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/WON.0000000000000390"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijnurstu.2017.03.012"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/WON.0000000000000656"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/nicc.12331"},{"key":"e_1_2_9_11_1","article-title":"Interventions for preventing and treating incontinence\u2010associated dermatitis in adults","volume":"11","author":"Beeckman D","year":"2016","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijnurstu.2019.103509"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.12968\/nrec.2017.19.6.321"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.12968\/bjon.2018.27.Sup20.S34"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/iwj.12906"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.12968\/bjon.2001.10.Sup1.5346"},{"issue":"12","key":"e_1_2_9_17_1","first-page":"44","article-title":"An evaluation of two incontinence skin care protocols in a long\u2010term care setting","volume":"48","author":"Lewis\u2010Byers K","year":"2002","journal-title":"Ostomy Wound Manage"},{"key":"e_1_2_9_18_1","unstructured":"BeeckmanD CampbellJ CampbellK.Incontinence associated dermatitis: moving prevention forward. Paper presented at the Proceedings of the Global IAD Expert Panel: Wounds International;2015.https:\/\/www.woundsinternational.com\/resources\/details\/incontinence\u2010associated\u2010dermatitis\u2010moving\u2010prevention\u2010forward"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.2165\/11311010-000000000-00000"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.12968\/bjon.2013.22.8.450"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.12968\/bjcn.2020.25.Sup3.S12"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsapm.9b01214"},{"key":"e_1_2_9_23_1","unstructured":"Research Randomizer [computer program]. 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