{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T12:53:27Z","timestamp":1779886407982,"version":"3.53.1"},"reference-count":44,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2021,10,29]],"date-time":"2021-10-29T00:00:00Z","timestamp":1635465600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2021,10,29]],"date-time":"2021-10-29T00:00:00Z","timestamp":1635465600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100012190","name":"Ministry of Science and Higher Education of the Russian Federation","doi-asserted-by":"publisher","award":["075\u201015\u20102020\u2010926"],"award-info":[{"award-number":["075\u201015\u20102020\u2010926"]}],"id":[{"id":"10.13039\/501100012190","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["International Wound Journal"],"published-print":{"date-parts":[[2022,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    A growing number of studies report dermal malignancies mimicking diabetic foot ulcers (DFUs). We reviewed clinical cases reporting malignant tumours misdiagnosed to be DFU aiming to identify factors contributing to misdiagnosis. We systematically searched in PubMed for clinical cases reporting on misdiagnosis of DFU in patients with cancer. A chi\u2010square analysis was conducted to show the link between the incidence of initial DFU misdiagnosis and patient age, gender and wound duration. Lesions misdiagnosed to be DFU were subsequently diagnosed as melanoma (68% of the cases), Kaposi's sarcoma (14%), squamous cell carcinoma (11%), mantle cell lymphoma, and diffuse B\u2010cell lymphoma (both by 4%). Older age (\u226565\u2009years) was associated with a significantly increased risk of malignancy masked as DFU (OR: 2.452; 95% CI: 1.132 to 5.312;\n                    <jats:italic>P<\/jats:italic>\n                    value\u00a0=\u00a0.019). The risk of such suspicion in older patients (age\u2009\u2265\u200965\u2009years) was 145% higher than in younger patients (age\u2009&lt;\u200965\u2009years). Clinicians should maintain a high level of awareness towards potentially malignant foot lesions in elderly patients with diabetes (age\u2009\u2265\u200965).\n                  <\/jats:p>","DOI":"10.1111\/iwj.13688","type":"journal-article","created":{"date-parts":[[2021,10,29]],"date-time":"2021-10-29T07:40:16Z","timestamp":1635493216000},"page":"871-887","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["Misdiagnosis of diabetic foot ulcer in patients with undiagnosed skin malignancies"],"prefix":"10.1111","volume":"19","author":[{"given":"Alexey V.","family":"Lyundup","sequence":"first","affiliation":[{"name":"Peoples' Friendship University of Russia  Moscow Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maxim V.","family":"Balyasin","sequence":"additional","affiliation":[{"name":"Peoples' Friendship University of Russia  Moscow Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nadezhda V.","family":"Maksimova","sequence":"additional","affiliation":[{"name":"Sechenov First Moscow State Medical University (Sechenov University)  Moscow Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marina V.","family":"Kovina","sequence":"additional","affiliation":[{"name":"Peoples' Friendship University of Russia  Moscow Russia"},{"name":"AltraVita IVF Clinic  Moscow Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mikhail E.","family":"Krasheninnikov","sequence":"additional","affiliation":[{"name":"Peoples' Friendship University of Russia  Moscow Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tatiana G.","family":"Dyuzheva","sequence":"additional","affiliation":[{"name":"Sechenov First Moscow State Medical University (Sechenov University)  Moscow Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sergey A.","family":"Yakovenko","sequence":"additional","affiliation":[{"name":"AltraVita IVF Clinic  Moscow Russia"},{"name":"Department of Biophysics Faculty of Physics, Lomonosov's Moscow State University  Moscow Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Svetlana A.","family":"Appolonova","sequence":"additional","affiliation":[{"name":"Sechenov First Moscow State Medical University (Sechenov University)  Moscow Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helgi B.","family":"Schi\u00f6th","sequence":"additional","affiliation":[{"name":"Sechenov First Moscow State Medical University (Sechenov University)  Moscow Russia"},{"name":"Department of Neuroscience, Functional Pharmacology Uppsala University  Uppsala Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2888-7999","authenticated-orcid":false,"given":"Ilya D.","family":"Klabukov","sequence":"additional","affiliation":[{"name":"National Medical Research Radiological Center  Obninsk Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,10,29]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1080\/07853890.2016.1231932"},{"issue":"7","key":"e_1_2_10_3_1","first-page":"857","article-title":"Type 2 diabetes mellitus and risk of malignant melanoma: a systematic review and meta\u2010analysis of cohort studies","volume":"43","author":"Qi L","year":"2014","journal-title":"Iran J Public Health"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/md.0000000000004070"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/iwj.12481"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1177\/1534734611412001"},{"issue":"12","key":"e_1_2_10_7_1","first-page":"E125","article-title":"Malignant transformation of a site of prior diabetic foot ulceration to Verrucous carcinoma: a case report","volume":"29","author":"Priesand SJ","year":"2017","journal-title":"Wounds"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/md.0000000000004332"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-5491.2010.03102.x"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1067\/mjd.2003.63"},{"key":"e_1_2_10_11_1","unstructured":"SmithNephew Regranex. 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