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This problem is mainly related to inadequate medical care and awareness. No community or race is immune. The underlying malignant transformation mechanism remains unclear. The study aims, according to our experience, to review the prognostic factors through the management protocol of Marjolin's ulcers. This prospective study was conducted in the Aswan University Plastic &amp; Burn surgery department in South Egypt between 2013 and 2020 and investigated 226 patients with chronic post\u2010burn ulceration. Nineteen cases were proved to have Marjolin's ulcer, and the other cases that had been excluded from being malignant went for reconstruction with split\u2010thickness skin graft with\/without flap after adequate ulcer debridement. The surgical, oncologic, radiologic indications, and prognostic factors were reviewed according to our management outcome\u2014the assessment with follow\u2010up period extended over 5\u2009years. Histopathology of ulcers ranged among mild, moderate, and poorly differentiated squamous cell carcinoma. One scalp ulcer case showed basosquamous pathology. Most cases presented at age above 50, but no age was immune. The mean latent period was 29\u2009years on average. The lesions' sites varied in their anatomic location where they involved the upper extremity, the scalp, and the lower extremity that had a predilection. Although surgical excision is the primary management line for tumour ablation, other factors may change the management course. During the follow\u2010up period, neoplasm recurrence in the form of lymph node enlargement and\/or locoregional metastasis was detected in eight cases. Within 1\u2009year after the intervention, six recurrent cases died, and two were saved. In addition to the case study, this paper reviewed the literature and provided our team a good experience in light of the NCCN protocol for non\u2010melanotic cutaneous carcinoma, although we suffered limited medical resources. It is concluded that early accurate diagnosis, low\u2010grade malignancy, and well\u2010planned individualised surgery with adjuvant radiotherapy were the best prognostic factors. The close follow\u2010up for an early sign of disease recurrence is paramount.<\/jats:p>","DOI":"10.1111\/iwj.13690","type":"journal-article","created":{"date-parts":[[2021,9,18]],"date-time":"2021-09-18T04:58:31Z","timestamp":1631941111000},"page":"895-909","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["EXPRESSION OF CONCERN: Post\u2010burn scar malignancy: 5\u2010year management review and experience"],"prefix":"10.1111","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2872-361X","authenticated-orcid":false,"given":"Ahmed K.","family":"Mousa","sequence":"first","affiliation":[{"name":"Plastic &amp; Reconstructive Surgery \u2010 Medical School of Aswan University  Aswan Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1655-6519","authenticated-orcid":false,"given":"Anwar A.","family":"Elshenawy","sequence":"additional","affiliation":[{"name":"Surgical Oncology Aswan University  Aswan Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3595-4077","authenticated-orcid":false,"given":"Salah M.","family":"Maklad","sequence":"additional","affiliation":[{"name":"Radiology Department Medical School of Aswan University  Aswan Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8415-5824","authenticated-orcid":false,"given":"Shaimaa M. 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