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Point\u2010of\u2010care fluorescence imaging detects elevated bacterial burden in and around wounds with high sensitivity. This prospective observational study examined the impact of incorporating fluorescence imaging into standard care for diagnosis and management of wound\u2010related cellulitis. Two hundred thirty\u2010six patients visiting an outpatient wound care centre between January 2020 and April 2021 were included in this study. Patients underwent routine fluorescence scans for bacteria (range: 1\u201048 scans\/patient). Wound\u2010related cellulitis was diagnosed in 6.4% (15\/236) of patients. In these patients, fluorescence scans showed an irregular pattern of red (bacterial) fluorescence extending beyond the wound bed and periwound that could not be removed through cleansing or debridement, indicating the invasive extension of bacteria (wound\u2010related cellulitis). Point\u2010of\u2010care identification facilitated rapid initiation of treatments (source control and antibiotics, when warranted) that resolved the fluorescence. No patients had worsening of cellulitis requiring intravenous antibiotics and\/or hospitalisation. These findings demonstrate the utility of point\u2010of\u2010care fluorescence imaging for efficient detection and proactive, targeted management of wound\u2010related cellulitis.<\/jats:p>","DOI":"10.1111\/iwj.13696","type":"journal-article","created":{"date-parts":[[2021,10,7]],"date-time":"2021-10-07T15:06:34Z","timestamp":1633619194000},"page":"996-1008","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["Diagnosis and treatment of the invasive extension of bacteria (cellulitis) from chronic wounds utilising <scp>point\u2010of\u2010care<\/scp> fluorescence imaging"],"prefix":"10.1111","volume":"19","author":[{"given":"Charles A.","family":"Andersen","sequence":"first","affiliation":[{"name":"Vascular\/Endovascular\/Limb Preservation Surgery Service Madigan Army Medical Center  Joint Base Lewis\u2010McChord Washington 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