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This cross\u2010sectional correlational study conducted at the cardiovascular and plastic surgery clinics of a regional teaching hospital between August 2019 and June 2020 investigates venous clinical severity, pain, fatigue, depression, sleep quality, quality of life, and related factors among 167 patients with VLUs. The potential predictors of the quality of life in terms of activities were venous clinical severity (<jats:italic>P<\/jats:italic>\u00a0&lt;\u20090.001), pain (<jats:italic>P<\/jats:italic>\u00a0=\u20090.004), and fatigue (<jats:italic>P<\/jats:italic>\u00a0&lt;\u20090.001) after adjusting for covariates. The potential predictors of the quality of life in terms of the psychological domain were marital status (single\/divorced) (<jats:italic>P<\/jats:italic>\u00a0=\u20090.016), marital status (widowed) (<jats:italic>P<\/jats:italic>\u00a0=\u20090.027), venous clinical severity (<jats:italic>P<\/jats:italic>\u00a0&lt;\u20090.001), pain (<jats:italic>P<\/jats:italic>\u00a0=\u20090.001), and fatigue (<jats:italic>P<\/jats:italic>\u00a0=\u20090.002). The potential predictors of the quality of life with regard to symptoms were venous clinical severity (<jats:italic>P<\/jats:italic>\u00a0&lt;\u20090.001), pain (<jats:italic>P<\/jats:italic>\u00a0&lt;\u20090.001), fatigue (<jats:italic>P<\/jats:italic>\u00a0=\u20090.001), and depression (<jats:italic>P<\/jats:italic>\u00a0=\u20090.038). These potential predictors can serve as the basis of interventions for patients with VLUs, such as those related to nutrition or training in wound dressing.<\/jats:p>","DOI":"10.1111\/iwj.13700","type":"journal-article","created":{"date-parts":[[2021,10,8]],"date-time":"2021-10-08T04:13:38Z","timestamp":1633666418000},"page":"1039-1050","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Potential predictors of quality of life in patients with venous leg ulcers: A cross\u2010sectional study in Taiwan"],"prefix":"10.1111","volume":"19","author":[{"given":"Hsiao\u2010Ching","family":"Lin","sequence":"first","affiliation":[{"name":"Department of Surgery, Division of Plastic Surgery, Wound Care Center Ditmanson Medical Foundation Chia\u2010Yi Christian Hospital  Chia\u2010Yi 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