{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T11:01:19Z","timestamp":1788865279524,"version":"build-2803163510"},"reference-count":48,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2022,1,13]],"date-time":"2022-01-13T00:00:00Z","timestamp":1642032000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["International Wound Journal"],"published-print":{"date-parts":[[2022,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Negative pressure wound therapy with instillation (NPWTi) has the dual function of negative pressure sealing drainage and irrigation, which overcomes the disadvantages of NPWT, such as tube obstruction, inability to apply topical medicine, and poor anti\u2010infection ability. NPWTi has been researched extensively and widely used in various types of wounds, and certain effects have been achieved. A series of parameters for NPWTi have not been unified at present, including the flushing fluid option, flushing mode, and treatment period. This paper reviews the research progress of these parameters for NPWTi and their application in the treatment of orthopaedic wounds.<\/jats:p>","DOI":"10.1111\/iwj.13741","type":"journal-article","created":{"date-parts":[[2022,1,14]],"date-time":"2022-01-14T03:43:12Z","timestamp":1642131792000},"page":"1449-1455","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Research progress on negative pressure wound therapy with instillation in the treatment of orthopaedic wounds"],"prefix":"10.1111","volume":"19","author":[{"given":"Lijiao","family":"Wu","sequence":"first","affiliation":[{"name":"Department of Orthopedic Surgery Fujian Provincial Hospital Jinshan Branch  Fuzhou China"},{"name":"Shengli Clinical Medical College Fujian Medical University  Fuzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Baoyu","family":"Wen","sequence":"additional","affiliation":[{"name":"Department of Orthopedic 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