{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T07:09:14Z","timestamp":1767164954762,"version":"build-2238731810"},"reference-count":49,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2022,7,19]],"date-time":"2022-07-19T00:00:00Z","timestamp":1658188800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["International Wound Journal"],"published-print":{"date-parts":[[2023,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    We performed a meta\u2010analysis to evaluate the effect of low\u2010frequency ultrasound as an added treatment for chronic wounds. A systematic literature search up to May 2022 was performed and 838 subjects with chronic wounds at the baseline of the studies; 412 of them were using the low\u2010frequency ultrasound (225 low\u2010frequency high\u2010intensity contact ultrasound for diabetic foot wound ulcers, and 187 low\u2010frequency low\u2010intensity non\u2010contact ultrasound for a venous leg wound ulcers), and 426 were using standard care (233 sharp debridements for diabetic foot wound ulcers and 193 sham treatments for venous leg wound ulcers). Odds ratio (OR), and mean difference (MD) with 95% confidence intervals (CIs) were calculated to assess the effect of low\u2010frequency ultrasound as an added treatment for chronic wounds using the dichotomous, and contentious methods with a random or fixed\u2010effect model. The low\u2010frequency high\u2010intensity contact ultrasound for diabetic foot wound ulcers had significantly lower non\u2010healed diabetic foot wound ulcers at \u22653\u2009months (OR, 0.37; 95% CI, 0.24\u20100.56,\n                    <jats:italic>P<\/jats:italic>\n                    \u2009&lt;\u2009.001), a higher percentage of diabetic foot wound ulcers area reduction (MD, 17.18; 95% CI, 6.62\u201027.85,\n                    <jats:italic>P<\/jats:italic>\n                    \u00a0=\u00a0.002) compared with sharp debridement for diabetic foot wound ulcers. The low\u2010frequency low\u2010intensity non\u2010contact ultrasound for a venous leg wound ulcers had a significantly lower non\u2010healed venous leg wound ulcers at \u22653\u2009months (OR, 0.31; 95% CI, 0.15\u20100.62,\n                    <jats:italic>P<\/jats:italic>\n                    \u00a0=\u00a0.001), and higher percentage venous leg wound ulcers area reduction (MD, 18.96; 95% CI, 2.36\u201035.57,\n                    <jats:italic>P<\/jats:italic>\n                    \u00a0=\u00a0.03) compared with sham treatments for a venous leg wound ulcers. The low\u2010frequency ultrasound as an added treatment for diabetic foot wound ulcers and venous leg wound ulcers had significantly lower non\u2010healed chronic wound ulcers at \u22653\u2009months, a higher percentage of chronic wound ulcers area reduction compared with standard care. The analysis of outcomes should be with caution because of the low sample size of all the 17 studies in the meta\u2010analysis and a low number of studies in certain comparisons.\n                  <\/jats:p>","DOI":"10.1111\/iwj.13893","type":"journal-article","created":{"date-parts":[[2022,7,19]],"date-time":"2022-07-19T06:44:40Z","timestamp":1658213080000},"page":"448-457","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["RETRACTED: The efficacy of low\u2010frequency ultrasound as an added treatment for chronic wounds: A meta\u2010analysis"],"prefix":"10.1111","volume":"20","author":[{"given":"Haiting","family":"Chen","sequence":"first","affiliation":[{"name":"Department of Emergency Medical Center Affiliated Hospital of Guangdong Medical University  Guangdong China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhenxing","family":"Yu","sequence":"additional","affiliation":[{"name":"Department of Pulmonary and Critical Care Medicine, Wuhan Jinyintan Hospital Tongji Medical College of Huazhong University of Science and Technology; Hubei Clinical Research Center for Infectious Diseases; Wuhan Research Center for Communicable Disease Diagnosis and Treatment, Chinese Academy of Medical Sciences; Joint Laboratory of Infectious Diseases and Health, Wuhan Institute of Virology and Wuhan Jinyintan Hospital, Chinese Academy of Sciences  Hubei China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ning","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Ultrasonic Imaging the Fifth Hospital of Wuhan  Hubei China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jianbin","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Ultrasonic Imaging the Fifth Hospital of Wuhan  Hubei China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xia","family":"Liang","sequence":"additional","affiliation":[{"name":"Department of Nursing Department Affiliated Hospital of Guangdong Medical University  Guangdong China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoling","family":"Liang","sequence":"additional","affiliation":[{"name":"Department of Nursing Department Affiliated Hospital of Guangdong Medical University  Guangdong China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meixia","family":"Liang","sequence":"additional","affiliation":[{"name":"Department of Gastrointestinal Surgery Affiliated Hospital of Guangdong Medical University  Guangdong China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Minghui","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics the Fifth Hospital of Wuhan  Hubei China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2946-8451","authenticated-orcid":false,"given":"Jiang","family":"Ni","sequence":"additional","affiliation":[{"name":"Department of Pharmacy the Fifth Hospital of Wuhan  Hubei China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,7,19]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1524-475X.1994.20305.x"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-475X.2008.00427.x"},{"key":"e_1_2_9_4_1","article-title":"Therapeutic ultrasound for venous leg ulcers","volume":"5","author":"Cullum N","year":"2017","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1524-475X.1998.60205.x"},{"key":"e_1_2_9_6_1","article-title":"Debridement for surgical wounds","volume":"9","author":"Smith F","year":"2013","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.dental.2005.02.003"},{"key":"e_1_2_9_8_1","unstructured":"BradleyM CullumN SheldonT.The Debridement of Chronic Wounds: a Systematic Review. 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