{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T18:38:16Z","timestamp":1792175896081,"version":"4.4.0"},"reference-count":34,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2022,8,8]],"date-time":"2022-08-08T00:00:00Z","timestamp":1659916800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["International Wound Journal"],"published-print":{"date-parts":[[2023,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Chronic wounds are associated with significant clinical, economic and quality\u2010of\u2010life burden. Despite the variety of wound imaging systems available in the market for wound assessment and surveillance, few are clinically validated among patients of Asian ethnicity. We aimed to clinically validate the accuracy of a smartphone wound application (Tissue Analytics [TA], Net Health Systems Inc, Florida, USA), versus conventional wound measurements (visual approximation and paper rulers), in patients of Asian ethnicity with venous leg ulcers (VLU). A prospective cohort study of patients presenting with VLU to a specialist wound nurse clinic over a 5\u2010week duration was conducted. Each patient received seven wound measurements: one by a trained wound nurse clinician, and three separate wound measurements using TA on each of the iOS and Android operating systems. Inter\u2010rater and intra\u2010rater reliability between clinical and TA\u2010based measurements were analysed using intra\u2010class correlation statistics, with values of &lt;0.5, 0.5 to 0.75, 0.75 to 0.9, and &gt;0.9 indicating poor, moderate, good and excellent reliability, respectively. 82 patients (51% males), with a mean age at 65.8\u2009years, completed the 5\u2010week study duration. 25 (30%) had underlying diabetes mellitus. Chinese, Malay and Indian ethnicity comprised 68%, 12% and 11%, respectively. The VLU healed in 26 (32%) of patients within the study period. In total, 358 wound episodes with 2334 wound images were analysed. Inter\u2010rater reliability for length, width and area between wound nurse measurements and TA application measurements was good (range 0.799\u20100.919, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001). Separate measurements of intra\u2010rater reliability for length, width and area within the iOS or Android systems were excellent (range 0.967\u20100.985 and range 0.977\u20100.984 respectively, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001). Inter\u2010rater reliability between TA used on the iOS and Android systems was also excellent (0.987\u20100.989, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001). Tissue Analytics, a smartphone wound application, is a useful adjunct for wound assessment and surveillance in VLU patients of Asian ethnicity.<\/jats:p>","DOI":"10.1111\/iwj.13918","type":"journal-article","created":{"date-parts":[[2022,8,9]],"date-time":"2022-08-09T04:16:35Z","timestamp":1660018595000},"page":"751-760","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["Clinical validation of a smartphone application for automated wound measurement in patients with venous leg ulcers"],"prefix":"10.1111","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8194-0800","authenticated-orcid":false,"given":"Khi Yung","family":"Fong","sequence":"first","affiliation":[{"name":"Yong Loo Lin School of Medicine National University of Singapore  Singapore Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tina Peiting","family":"Lai","sequence":"additional","affiliation":[{"name":"Wound and Stoma Care, Nursing Service Tan Tock Seng Hospital  Singapore Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9533-801X","authenticated-orcid":false,"given":"Kai Siang","family":"Chan","sequence":"additional","affiliation":[{"name":"Vascular Surgery Service, Department of General Surgery Tan Tock Seng Hospital  Singapore Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabel Jia Le","family":"See","sequence":"additional","affiliation":[{"name":"Vascular Surgery Service, Department of General Surgery Tan Tock Seng Hospital  Singapore Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cheng Cheng","family":"Goh","sequence":"additional","affiliation":[{"name":"Wound and Stoma Care, Nursing Service Tan Tock Seng Hospital  Singapore Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sivakami","family":"Muthuveerappa","sequence":"additional","affiliation":[{"name":"Wound and Stoma Care, Nursing Service Tan Tock Seng Hospital  Singapore Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Audrey Huimin","family":"Tan","sequence":"additional","affiliation":[{"name":"Wound and Stoma Care, Nursing Service Tan Tock Seng Hospital  Singapore Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shanying","family":"Liang","sequence":"additional","affiliation":[{"name":"Department of Surgery Woodlands Health  Singapore Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2289-5266","authenticated-orcid":false,"given":"Zhiwen Joseph","family":"Lo","sequence":"additional","affiliation":[{"name":"Department of Surgery Woodlands Health  Singapore Singapore"},{"name":"Lee Kong Chian School of Medicine Nanyang Technological University  Singapore Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,8,8]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/jech.53.3.149"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.113.006898"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1177\/000331970105200102"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9610(98)00169-X"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1177\/000331979704800111"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1742-481X.2010.00660.x"},{"issue":"4","key":"e_1_2_10_8_1","first-page":"439","article-title":"The importance of chronic venous insufficiency. 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