{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,12]],"date-time":"2026-06-12T15:47:28Z","timestamp":1781279248405,"version":"3.54.1"},"reference-count":29,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2022,9,13]],"date-time":"2022-09-13T00:00:00Z","timestamp":1663027200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001348","name":"Agency for Science, Technology and Research","doi-asserted-by":"publisher","award":["H1901a00Y9"],"award-info":[{"award-number":["H1901a00Y9"]}],"id":[{"id":"10.13039\/501100001348","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001348","name":"Agency for Science, Technology and Research","doi-asserted-by":"publisher","award":["H1901a0CC9"],"award-info":[{"award-number":["H1901a0CC9"]}],"id":[{"id":"10.13039\/501100001348","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["International Wound Journal"],"published-print":{"date-parts":[[2023,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Healthcare costs arising from venous leg ulcers (VLU) are expected to increase due to an aging population and increased prevalence of comorbidities. We aim to estimate the healthcare resources incurred by VLU patients, and to quantify the extent to which predictors explain variation in cost\u2010related outcomes. Retrospective patient\u2010level cohort data for VLU patients were analysed using generalised linear regression models. Data were extracted from a tertiary hospital registry in Singapore, between 2013 and 2017. The outcome variables were length of stay per admission; inpatient and outpatient bill per admission; whether a patient underwent a surgical treatment of the venous system; and, whether they visited the emergency department. Cost outcomes were reported in Singapore dollars (S$). A total of 162 VLU patients were included with a mean age of 67.5 (\u00b114.4). For the inpatient setting the mean length of stay was 8.1\u2009days and the mean inpatient bill was S$7886. For outpatients, the mean number of dressings was 29.4, and mean outpatient bill was S$6962. Heart disease patients incurred longer hospital stays and larger inpatient bills per admission and females had greater odds of undergoing a surgical procedure on the venous system. Certain VLU patient groups were found to be associated with larger cost outcomes.<\/jats:p>","DOI":"10.1111\/iwj.13931","type":"journal-article","created":{"date-parts":[[2022,9,13]],"date-time":"2022-09-13T11:48:05Z","timestamp":1663069685000},"page":"845-852","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["The burden of costs on health services from patients with venous leg ulcers in Singapore"],"prefix":"10.1111","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1935-5499","authenticated-orcid":false,"given":"Nuraini","family":"Nazeha","sequence":"first","affiliation":[{"name":"Health Services and Systems Research Duke\u2010NUS Medical School  Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jia Yi","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Surgery, Yong Loo Lin School of Medicine National University of Singapore  Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6473-4375","authenticated-orcid":false,"given":"Seyed Ehsan","family":"Saffari","sequence":"additional","affiliation":[{"name":"Health Services and Systems Research Duke\u2010NUS Medical School  Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0205-6801","authenticated-orcid":false,"given":"Lingyan","family":"Meng","sequence":"additional","affiliation":[{"name":"Department of Surgery, Yong Loo Lin School of Medicine National University of Singapore  Singapore"},{"name":"Department of Cardiac, Thoracic and Vascular Surgery National University Health System  Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4560-2374","authenticated-orcid":false,"given":"Pei","family":"Ho","sequence":"additional","affiliation":[{"name":"Department of Surgery, Yong Loo Lin School of Medicine National University of Singapore  Singapore"},{"name":"Department of Cardiac, Thoracic and Vascular Surgery National University Health System  Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi Zhen","family":"Ng","sequence":"additional","affiliation":[{"name":"Wound Care Innovation for the Tropics Programme Skin Research Institute of Singapore, A*STAR  Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5559-3267","authenticated-orcid":false,"given":"Nicholas","family":"Graves","sequence":"additional","affiliation":[{"name":"Health Services and Systems Research Duke\u2010NUS Medical School  Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,9,13]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/413604"},{"key":"e_1_2_9_3_1","volume-title":"Chronic Wound Care Guideline","author":"The Wound 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