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This evaluation assessed the early response of different hard\u2010to\u2010heal wounds to a simple, wearable, single\u2010use, automated microcurrent EST device (Accel\u2010Heal, Accel\u2010Heal Technologies Limited \u2010 Hever, UK). Forty wounds (39 patients: 18 female \u2010 21 male), mean age 68.9\u2009\u00b1\u200914.0\u2009years comprised of: seven post\u2010surgical, three trauma, 12 diabetic foot (DFU), 10 venous (VLU), four pressure injuries (PI), four mixed venous or arterial ulcers (VLU\/arterial) received automated microcurrent EST for 12\u2009days. Early clinical responses were scored on a 0\u20135 scale (5\u2010excellent\u20140\u2010no response). Pain was assessed at 48\u2009h, seven\u2009days, and 14\u2009days on a 0\u201310 visual analogue scale (VAS). Overall, 78% of wounds showed a marked positive clinical response (scores of 5 and 4). Sixty eight percent of wounds were painful with a mean VAS score of 5.5. Almost every patient (96%) with pain experienced reduction within 48\u2009h. All patients with painful wounds experienced pain reduction after seven\u2009days: 2.50 VAS (45% reduction) and further pain reduction after 14\u2009days: 1.83 VAS (33%).<\/jats:p>","DOI":"10.1111\/iwj.14071","type":"journal-article","created":{"date-parts":[[2023,1,5]],"date-time":"2023-01-05T08:05:58Z","timestamp":1672905958000},"page":"2053-2061","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Activation of healing and reduction of pain by single\u2010use automated microcurrent electrical stimulation therapy in patients with hard\u2010to\u2010heal wounds"],"prefix":"10.1111","volume":"20","author":[{"given":"Peter","family":"Kurz","sequence":"first","affiliation":[{"name":"WPM Wund Pflege Management GmbH  Bad Pirawarth Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriele","family":"Danner","sequence":"additional","affiliation":[{"name":"WPM Wund Pflege Management GmbH  Bad Pirawarth Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean\u2010Paul","family":"Lembelembe","sequence":"additional","affiliation":[{"name":"Department, Geriatrics &amp; Wound Day Hospital Clinique des Augustines  Malestroit France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"HariKrishna K. 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