{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T09:17:04Z","timestamp":1788254224086,"version":"build-2803163510"},"reference-count":25,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2023,2,6]],"date-time":"2023-02-06T00:00:00Z","timestamp":1675641600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100009592","name":"Beijing Municipal Science and Technology Commission","doi-asserted-by":"publisher","award":["Z191100006619009"],"award-info":[{"award-number":["Z191100006619009"]}],"id":[{"id":"10.13039\/501100009592","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81871538"],"award-info":[{"award-number":["81871538"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["International Wound Journal"],"published-print":{"date-parts":[[2023,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Keloid infections reduce patient\u2010reported quality of life greatly. Characteristics and risk factors of keloid infections have not been thoroughly studied. So, a retrospective cohort study was conducted focusing on the potential risk factors, microbiologic cultures and histological findings. Keloid patients consulting for surgical interventions were included in this study. Data were collected from their electronic medical records. 564 patients were recruited with the keloid infection rate being 22.4%. For adult patients, age above 40\u2009years (OR, 2.84; <jats:italic>P<\/jats:italic>\u00a0=\u2009.000), disease duration of 12\u2009years or more (OR, 3.03; <jats:italic>P<\/jats:italic>\u00a0=\u2009.000), the number of keloids over 3 (OR, 1.59; <jats:italic>P<\/jats:italic>\u00a0=\u2009.050) and the presence of family history (OR, 1.91; <jats:italic>P<\/jats:italic>\u00a0=\u2009.027) were significantly associated with keloid infections. Suppurative keloids were located mostly in thorax (61.79%). For the under\u2010age subgroup(n\u00a0=\u00a025), family history was frequently seen in patients with infections. Microbiologic cultures revealed a mixed spectrum of bacteria including Staphylococcus (25%), Actinomyces (30%) and Prevotella (10%). The rate of epidermoid cysts was 19.7% in histological examination. Age &gt;\u200940\u2009years, disease duration \u226512\u2009years, the number of keloids &gt;3 and the presence of family history are risk factors for keloid infections.<\/jats:p>","DOI":"10.1111\/iwj.14099","type":"journal-article","created":{"date-parts":[[2023,2,7]],"date-time":"2023-02-07T03:28:12Z","timestamp":1675740492000},"page":"2215-2223","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Risk factors associated with keloid infections: A five\u2010year retrospective study"],"prefix":"10.1111","volume":"20","author":[{"given":"Zhengyun","family":"Liang","sequence":"first","affiliation":[{"name":"Department of Plastic Surgery Peking Union Medical College Hospital  Beijing China"},{"name":"Chinese Academy of Medical Sciences &amp; Peking Union Medical College  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mingzi","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery Peking Union Medical College Hospital  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Hao","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery Peking Union Medical College Hospital  Beijing China"},{"name":"Chinese Academy of Medical Sciences &amp; Peking Union Medical College  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mengjie","family":"Shan","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery Peking Union Medical College Hospital  Beijing China"},{"name":"Chinese Academy of Medical Sciences &amp; Peking Union Medical College  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hao","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery Peking Union Medical College Hospital  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yijun","family":"Xia","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery Peking Union Medical College Hospital  Beijing China"},{"name":"Chinese Academy of Medical Sciences &amp; Peking Union Medical College  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiao","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery Peking Union Medical College Hospital  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guojing","family":"Chang","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery Peking Union Medical College Hospital  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Youbin","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery Peking Union Medical College Hospital  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,2,6]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0041-1731461"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms18030606"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2020.603187"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.2147\/JIR.S312091"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clindermatol.2014.04.004"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/ijd.15641"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.1978.tb00438.x"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.trsl.2021.05.006"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms23126820"},{"issue":"2","key":"e_1_2_11_11_1","first-page":"213","article-title":"Hypertension: a systemic key to understanding local keloid severity. 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