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A retrospective study of consecutive patients with post\u2010radiation ulcers at a single institute from 2012 to 2022 was conducted. Reconstruction included complete excision of irradiated tissue and coverage with well\u2010vascularised tissue, including local flaps, regional flaps and free flaps. Study outcomes included complications, reoperation rates, overall flap success and recurrence rates. Thirteen patients (six males and seven females; mean age, 56.85\u2009\u00b1\u200913.87\u2009years) with a mean 10\u2010month history of post\u2010radiation ulcers were enrolled. Ulcers are predominantly located in the chest (n\u2009=\u20093, 23.1%), head (n\u2009=\u20092, 15.4%) and neck (n\u2009=\u20092, 15.4%), with a mean size of 33.1\u00a0cm<jats:sup>2<\/jats:sup> (range from 1\u00a0cm<jats:sup>2<\/jats:sup> to 120\u2009cm<jats:sup>2<\/jats:sup>). Eleven patients underwent reconstruction with 15 regional flaps and three local flaps, one patient received a free anterolateral thigh fasciocutaneous flap and one patient underwent amputation. Among these 15 regional flaps, one (6.7%) had wound dehiscence and four (26.7%) had localised necrosis requiring reoperation. In addition, one patient with a non\u2010healing sinus tract underwent reoperation. The overall success rate of the regional flap was 100% and no recurrence was observed with a mean follow\u2010up of 23.3\u00a0months. Regional flaps seem a safe and effective reconstructive method for post\u2010radiation ulcers.<\/jats:p>","DOI":"10.1111\/iwj.14103","type":"journal-article","created":{"date-parts":[[2023,2,8]],"date-time":"2023-02-08T07:47:07Z","timestamp":1675842427000},"page":"2224-2232","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Regional flap: A reliable coverage for <scp>post\u2010radiation<\/scp> ulcer"],"prefix":"10.1111","volume":"20","author":[{"given":"Wenfang","family":"Dong","sequence":"first","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery Peking University Third Hospital  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinling","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery Peking University Third Hospital  Beijing 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