{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T07:06:36Z","timestamp":1767164796026,"version":"build-2238731810"},"reference-count":24,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2023,12,26]],"date-time":"2023-12-26T00:00:00Z","timestamp":1703548800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["International Wound Journal"],"published-print":{"date-parts":[[2024,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    This meta\u2010analysis investigates the effect of dexmedetomidine on postoperative wound healing in neurosurgical patients. A thorough literature search resulted in the selection of seven studies from an initial pool of 1546 records. The analysis focused on wound healing outcomes, evaluated by the Redness, Oedema, Ecchymosis, Discharge, Approximation (REEDA) scale and the Manchester Scar Scale (MSS). Results indicated significant improvements in the dexmedetomidine group: the REEDA scale scores at day seven post\u2010surgery showed a Standardized Mean Difference group (SMD\u2009=\u2009\u221216.18, 95% CI: [\u221222.30, \u221210.06],\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.01), and the MSS scores at 3\u2009months post\u2010operation demonstrated an (SMD\u2009=\u2009\u22128.95, 95% CI: [\u221214.27, \u22123.62],\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.01). These findings suggest that dexmedetomidine may enhance wound healing and reduce scar formation in neurosurgical patients. Bias assessment indicated a low risk of bias across the studies.\n                  <\/jats:p>","DOI":"10.1111\/iwj.14585","type":"journal-article","created":{"date-parts":[[2023,12,27]],"date-time":"2023-12-27T02:54:58Z","timestamp":1703645698000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["RETRACTED: The effect of dexmedetomidine on postoperative wound healing in neurosurgical patients: A meta\u2010analysis"],"prefix":"10.1111","volume":"21","author":[{"given":"Congying","family":"Zhu","sequence":"first","affiliation":[{"name":"Department of Anesthesiology Taizhou Hospital Affiliated to Wenzhou Medical University  Linhai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Donghang","family":"Cao","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology Taizhou Hospital Affiliated to Wenzhou Medical University  Linhai 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