{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T12:21:32Z","timestamp":1787314892408,"version":"build-2736575974"},"reference-count":38,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2023,12,27]],"date-time":"2023-12-27T00:00:00Z","timestamp":1703635200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["International Wound Journal"],"published-print":{"date-parts":[[2024,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>This study was to verify whether the severity of pressure injuries (PIs) in intensive care unit (ICU) patients plays a mediating role in the relationship between severity of their illnesses and risk of death. I examined adult patients admitted to the ICUs between 1 January 2014 and 31 August 2021. The average follow\u2010up period was 11.34\u2009months. A total of 390 ICU patients suffered from PIs. The influences of the APACHE II score of the ICU patients on the mediating variable \u2018unstageable &amp; DTPIs vs. Stage 1&amp;2 PIs\u2019 and on risk of death were significant. After controlling the influence of APACHE II score on risk of death, the influences of mediating variables \u2018Stage 3&amp;4 PIs vs. Stage 1&amp;2 PIs\u2019 and \u2018unstageable &amp; DTPIs vs. Stage 1&amp;2 PIs\u2019 on risk of death were also significant. The regression coefficient of APACHE II score of the ICU patients declined after the severity of PIs was included. The Sobel test on the indirect effects also reached the level of significance. The severity of illnesses is a factor that is beyond my control, severe PIs should still be prevented to lower the risk of death.<\/jats:p>","DOI":"10.1111\/iwj.14623","type":"journal-article","created":{"date-parts":[[2023,12,27]],"date-time":"2023-12-27T05:54:05Z","timestamp":1703656445000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Influence of severity of illnesses on risk of death in intensive care unit patients with severity of pressure injuries as mediating variable"],"prefix":"10.1111","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4906-2136","authenticated-orcid":false,"given":"Wen\u2010Pei","family":"Chang","sequence":"first","affiliation":[{"name":"Department of Nursing Shuang Ho Hospital, Taipei Medical University  New Taipei City Taiwan"},{"name":"School of Nursing College of Nursing, Taipei Medical University  Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,12,27]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amsu.2021.102318"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13054-014-0551-8"},{"issue":"3","key":"e_1_2_8_4_1","first-page":"189","article-title":"Prognosis of patients in a medical intensive care unit","volume":"2","author":"Unal AU","year":"2015","journal-title":"North Clin Istanb"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.5152\/TurkThoracJ.2018.18172"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/iwj.12879"},{"key":"e_1_2_8_7_1","volume-title":"Preventing Pressure Ulcers in Hospitals: A Toolkit for Improving Quality of Care","author":"Berlowitz D","year":"2014"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/iwj.13648"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.25270\/wmp.2020.2.1421"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2702.2008.02598.x"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtv.2019.02.001"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.aucc.2017.07.004"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000027380"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.4103\/ijccm.IJCCM_422_17"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1590\/0034-7167-2020-0062"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10096-018-3216-8"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-018-3076-y"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph17228543"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph18063226"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/iwj.13581"},{"issue":"2","key":"e_1_2_8_21_1","first-page":"111","article-title":"Retrospective evaluation of pressure sores of patients in intensive care","volume":"27","author":"Esen O","year":"2016","journal-title":"South Clin Ist Euras"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1097\/00003246-198510000-00009"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1988.03410120085032"},{"key":"e_1_2_8_24_1","unstructured":"National Pressure injury Advisory Panel. 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