{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,7]],"date-time":"2026-05-07T06:26:08Z","timestamp":1778135168233,"version":"3.51.4"},"reference-count":30,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2024,1,31]],"date-time":"2024-01-31T00:00:00Z","timestamp":1706659200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["International Wound Journal"],"published-print":{"date-parts":[[2024,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Evaluating complications and mortality risks in burn patients is crucial for effective treatment planning and improving survival rates. This study investigated the relationship between the serum vitamin D level and the clinical outcomes of adult burns patients. This was a prospective cohort of adult patients hospitalized due to thermal burns at a burn centre in the north of Iran. Based on the level of 25 hydroxyvitamin D measured upon admission, patients were divided into two groups of patients with sufficient 25 hydroxyvitamin D level and insufficient 25 hydroxyvitamin D level. Descriptive statistics were used for baseline demographics. Univariate analysis was conducted using Mann\u2013Whitney U, Chi\u2010square, independent samples, and Fisher's exact tests. A multivariate logistic regression was performed to adjust for the effects of confounding variables. Statistical analyses were conducted using SPSS 28.0 software. A total of 220 patients were included in the study. The average total body surface area burned was 30.52\u2009\u00b1\u20099.34. Patients with insufficient vitamin D levels had longer hospital stays (12.53 vs. 11.45) and longer stays in the intensive care unit (ICU) (3.32 vs. 2.40) than those with appropriate vitamin D levels. Participants with insufficient vitamin D levels exhibited a numerically higher incidence of infections than those with adequate levels (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.05). The multivariate regression found that vitamin D deficiency levels were associated with increased infection rates and prolonged hospital stay. This study suggests that vitamin D deficiency is a significant risk factor for adverse clinical outcomes in burn patients. Further research is needed to confirm these associations and to explore potential interventions to optimize vitamin D status in this patient population.\n                  <\/jats:p>","DOI":"10.1111\/iwj.14641","type":"journal-article","created":{"date-parts":[[2024,1,31]],"date-time":"2024-01-31T03:42:18Z","timestamp":1706672538000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Effect of vitamin D on clinical outcomes in patients with thermal injury"],"prefix":"10.1111","volume":"21","author":[{"given":"Sepide","family":"Pirdastan","sequence":"first","affiliation":[{"name":"Burn and Regenerative Medicine Research Center Guilan University of Medical Sciences  Rasht Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marjan","family":"Mahdavi Roshan","sequence":"additional","affiliation":[{"name":"Cardiovascular Disease Research Center, Department of Cardiology, Heshmat Hospital, School of Medicine Guilan University of Medical Sciences  Rasht Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammadreza","family":"Mobayen","sequence":"additional","affiliation":[{"name":"Burn and Regenerative Medicine Research Center Guilan University of Medical Sciences  Rasht Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Reza","family":"Asadzadegan","sequence":"additional","affiliation":[{"name":"Burn and Regenerative Medicine Research Center Guilan University of Medical Sciences  Rasht Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammad","family":"Ebrahim Ghafari","sequence":"additional","affiliation":[{"name":"Department of Biostatistics and Epidemiology, Faculty of Health Qom University of Medical Sciences  Qom Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seyed Amirhossein","family":"Mazhari","sequence":"additional","affiliation":[{"name":"Student Research Committee Azerbaijan Medical University  Baku Azerbaijan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5765-5647","authenticated-orcid":false,"given":"Mahsa","family":"Sadeghi","sequence":"additional","affiliation":[{"name":"Burn and Regenerative Medicine Research Center Guilan University of Medical Sciences  Rasht Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Parissa","family":"Bagheri Toolaroud","sequence":"additional","affiliation":[{"name":"Burn and Regenerative Medicine Research Center Guilan University of Medical Sciences  Rasht Iran"},{"name":"Health Information Management Research Center Kashan University of Medical Sciences  Kashan Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-3620-0977","authenticated-orcid":false,"given":"Hamidreza","family":"Alizadeh Otaghvar","sequence":"additional","affiliation":[{"name":"Trauma and Injury Research Center Iran University of Medical Sciences  Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,1,31]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/jbcr\/irab004"},{"issue":"2","key":"e_1_2_10_3_1","first-page":"104","article-title":"Suicidality after burn injuries: a significant overlooked challenge in burns survivors","volume":"1","author":"Doustahadi A","year":"2023","journal-title":"J Nurs Rep Clin Pract"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/iwj.14155"},{"issue":"3","key":"e_1_2_10_5_1","first-page":"150","article-title":"Burn survivors' challenges after hospital discharge: a neglected issue","volume":"1","author":"Doustahadi A","year":"2023","journal-title":"J Nurs Rep Clin Pract."},{"issue":"3","key":"e_1_2_10_6_1","first-page":"152","article-title":"Using virtual reality with morphine to reduce the pain of dressing change in burn patients","volume":"1","author":"Doustahadi A","year":"2023","journal-title":"J Nurs Rep Clin Pract"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.6061\/clinics\/2013(07)09"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1186\/s41038-018-0113-4"},{"key":"e_1_2_10_9_1","article-title":"The association between vitamin D levels and burn factors in different burn types. Burn","volume":"8","author":"Cho YS","year":"2020","journal-title":"Dent Traumatol"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/BCR.0000000000000445"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.29252\/wjps.10.1.60"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13054-014-0684-9"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13054-014-0660-4"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjsurg.2011.09.012"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0000000000000210"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1177\/0148607114566276"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12871-015-0063-3"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjsurg.2011.07.021"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.3109\/07853890.2015.1134807"},{"key":"e_1_2_10_20_1","first-page":"75","article-title":"The relationship between vitamin D, clinical outcomes and mortality rate in ICU patients: a prospective observational study","volume":"21","author":"Vosoughi N","year":"2016","journal-title":"J Res Med Sci off J Isfahan Univ Med Sci"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1038\/srep40646"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2011-0385"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.burns.2018.04.015"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1186\/s41038\u2010016\u20100054\u20108"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1186\/cc13790"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0b013e31822d74f3"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1186\/cc11252"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1002\/mnfr.201000174"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201408-1443ED"},{"key":"e_1_2_10_30_1","doi-asserted-by":"publisher","DOI":"10.1111\/iwj.14238"},{"key":"e_1_2_10_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.burns.2019.02.025"}],"container-title":["International Wound Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/iwj.14641","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,2]],"date-time":"2025-12-02T07:34:43Z","timestamp":1764660883000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/iwj.14641"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1,31]]},"references-count":30,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2024,2]]}},"alternative-id":["10.1111\/iwj.14641"],"URL":"https:\/\/doi.org\/10.1111\/iwj.14641","archive":["Portico"],"relation":{},"ISSN":["1742-4801","1742-481X"],"issn-type":[{"value":"1742-4801","type":"print"},{"value":"1742-481X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,1,31]]},"assertion":[{"value":"2023-11-25","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-12-17","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-01-31","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e14641"}}