{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T06:32:40Z","timestamp":1767162760281,"version":"build-2238731810"},"reference-count":38,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2024,1,17]],"date-time":"2024-01-17T00:00:00Z","timestamp":1705449600000},"content-version":"vor","delay-in-days":16,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["International Wound Journal"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Traumatic osteomyelitis with accompanying soft tissue defects presents a significant therapeutic challenge. This prospective, randomised controlled trial aims to evaluate the efficacy of antibiotic\u2010impregnated bone cement, flap coverage and negative pressure sealed irrigation in the management of traumatic osteomyelitis complicated by soft tissue defects. A total of 46 patients with clinically diagnosed traumatic osteomyelitis and soft tissue defects were randomised into a control group (\n                    <jats:italic>n<\/jats:italic>\n                    \u2009=\u200923) and an observation group (\n                    <jats:italic>n<\/jats:italic>\n                    \u2009=\u200923). The control group underwent standard flap coverage and negative\u2010pressure lavage, while the observation group received an additional treatment with antibiotic\u2010loaded bone cement. Efficacy was measured based on clinical criteria, surgical metrics and morphometric assessment of bone and soft tissue defects. Statistical analyses were performed using SPSS version 27.0. The observation group, treated with an integrated approach of flap coverage, negative pressure wound therapy (NPWT) and antibiotic\u2010impregnated bone cement, demonstrated significantly higher overall treatment efficacy (91.3%) compared to the control group, which received only flap coverage and NPWT (65.2%) (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.01). This enhanced efficacy was evidenced through various outcomes: the observation group experienced reduced surgical times, shorter hospital stays, fewer dressing changes and accelerated wound healing, all statistically significant (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.001). Additionally, a quantitative analysis at 6\u2010month post\u2010treatment revealed that the observation group showed more substantial reductions in both bone and soft tissue defect sizes compared to the control group (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.001). The multi\u2010modal treatment strategy, combining skin flap coverage, antibiotic bone cement and negative\u2010pressure irrigation, showed marked efficacy in treating traumatic osteomyelitis and associated soft tissue defects. This approach accelerated postoperative recovery and lowered costs.\n                  <\/jats:p>","DOI":"10.1111\/iwj.14650","type":"journal-article","created":{"date-parts":[[2024,1,17]],"date-time":"2024-01-17T19:04:41Z","timestamp":1705518281000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["RETRACTED: Evaluating the efficacy of combined flap coverage,\n                    <scp>antibiotic\u2010loaded<\/scp>\n                    bone cement and negative pressure irrigation in traumatic osteomyelitis management"],"prefix":"10.1111","volume":"21","author":[{"given":"Bo","family":"Cong","sequence":"first","affiliation":[{"name":"Department of Orthopedics Yantaishan Hospital Affiliated to Binzhou Medical University  Yantai China"},{"name":"Yantai Key Laboratory for Repair and Reconstruction of Bone &amp; Joint Yantaishan Hospital Affiliated to Binzhou Medical University  Yantai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-3316-9367","authenticated-orcid":false,"given":"Mingqi","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Orthopedics Yantaishan Hospital Affiliated to Binzhou Medical University  Yantai China"},{"name":"Yantai Key Laboratory for Repair and Reconstruction of Bone &amp; Joint Yantaishan Hospital Affiliated to Binzhou Medical University  Yantai China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,1,17]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cjtee.2021.07.006"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jor.2016.10.004"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.33073\/pjm-2023-024"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00934149"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.idc.2017.01.010"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/00003086-199903000-00005"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(04)16727-5"},{"key":"e_1_2_11_9_1","volume-title":"Osteomyelitis","author":"Momodu 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