{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,27]],"date-time":"2026-06-27T19:31:50Z","timestamp":1782588710036,"version":"3.54.5"},"reference-count":41,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["International Wound Journal"],"published-print":{"date-parts":[[2024,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Recent randomised controlled trials (RCTs) have investigated the analgesic activity of sesame oil among patients with limb trauma; nevertheless, their findings are inconsistent. Hence, this review aimed to clarify the impact of topical administration of sesame oil on acute pain of adult outpatients with minor limb trauma. The online databases (e.g., Scopus, PubMed, Web of Science) were searched up to 31 January 2024. The RCTs were included if they compared the effect of applying standard treatments plus topical sesame oil to administering standard treatments alone or with a placebo\/sham treatment. The Grading of Recommendations Assessment, Development, and Evaluation (GRADE) and the Cochrane Collaboration's risk of bias tool were applied to address the evidence quality and the study's methodological rigour, respectively. Four RCTs had the inclusion criteria, and their findings were pooled in a meta\u2010analysis employing a random\u2010effects approach. According to the pooled analysis, the reduction in mean change of the pain score from baseline to the second\/third intervention day was significantly higher in favour of clients who received standard care plus daily massage of the trauma site with sesame oil compared to those who received a control condition (weighted mean difference: \u22121.10; 95% confidence interval [\u22121.62, \u22120.57];\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.001). However, the evidence quality was moderate, and only two studies had good methodological rigour. Hence, more high\u2010quality studies are needed to make a solid evidence\u2010based conclusion about the favourable consequence of topical sesame oil on alleviating acute traumatic limb pain.\n                  <\/jats:p>","DOI":"10.1111\/iwj.14907","type":"journal-article","created":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T06:24:56Z","timestamp":1717223096000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Alleviating severity of limb trauma pain with coadministration of topical sesame oil and standard treatments: A GRADE\u2010assessed systematic review and meta\u2010analysis of randomised controlled trials"],"prefix":"10.1111","volume":"21","author":[{"given":"Omolbanin","family":"Razani","sequence":"first","affiliation":[{"name":"Department of Nursing Doroud Branch, Islamic Azad University  Doroud Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Morteza","family":"Nasiri","sequence":"additional","affiliation":[{"name":"Department of Anesthesia School of Allied Medical Sciences, Tehran University of Medical Sciences  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fatemeh","family":"Yarahmadi","sequence":"additional","affiliation":[{"name":"Department of Nursing Broujerd School of Nursing, Lorestan University of Medical Sciences  Khorramabad Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sahar","family":"Zonoori","sequence":"additional","affiliation":[{"name":"Department of Nursing Broujerd School of Nursing, Lorestan University of Medical Sciences  Khorramabad Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Afzal","family":"Shamsi","sequence":"additional","affiliation":[{"name":"Department of Anesthesia School of Allied Medical Sciences, Tehran University of Medical Sciences  Tehran Iran"},{"name":"Nursing and Midwifery Care Research Center Tehran University of Medical Sciences  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad","family":"Abbasi","sequence":"additional","affiliation":[{"name":"Department of Medical\u2010Surgical Nursing, School of Nursing and Midwifery Iran University of Medical Sciences  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3355-0821","authenticated-orcid":false,"given":"Masoomeh","family":"Asadi","sequence":"additional","affiliation":[{"name":"Department of Operating Room Nursing Abadan University of Medical Sciences  Abadan Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,6]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jfma.2021.02.008"},{"issue":"5","key":"e_1_2_10_3_1","first-page":"188","article-title":"Traumatic injuries in 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