{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,15]],"date-time":"2025-12-15T05:44:27Z","timestamp":1765777467985,"version":"3.48.0"},"reference-count":11,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2024,6,10]],"date-time":"2024-06-10T00:00:00Z","timestamp":1717977600000},"content-version":"vor","delay-in-days":9,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000664","name":"Health Technology Assessment Programme","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000664","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["International Wound Journal"],"published-print":{"date-parts":[[2024,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Diabetic foot ulcers (DFUs) often become infected and are treated with antimicrobials, with samples collected to inform care. Swab samples are easier than tissue sampling but report fewer organisms. Compared with culture and sensitivity (C&amp;S) methods, molecular microbiology identifies more organisms. Clinician perspectives on sampling and processing are unknown. We explored clinician perspectives on DFU sampling\u2014tissue samples\/wound swabs\u2014and on processing techniques, culture and sensitivity or molecular techniques. The latter provides information on organisms which have not survived transport to the laboratory for culture. We solicited feedback on molecular microbiology reports. Qualitative study using semi\u2010structured interview, with analysis using a Framework approach. CODIFI2 clinicians from UK DFU clinics. Seven consultants agreed to take part. They reported, overall, a preference for tissue samples over swabbing. Clinicians were not confident replacing C&amp;S with molecular microbiology as the approach to reporting was unfamiliar. The study was small and did not recruit any podiatrists or nurses, who may have discipline\u2010specific attitudes or perspectives on DFU care. Both sampling approaches appear to be used by clinicians. Molecular microbiology reports would not be, at present, suitable for replacement of traditional culture and sensitivity.<\/jats:p>","DOI":"10.1111\/iwj.14912","type":"journal-article","created":{"date-parts":[[2024,6,10]],"date-time":"2024-06-10T04:14:26Z","timestamp":1717992866000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Clinical perspectives on sampling and processing approaches for the management of infection in diabetic foot ulceration: A qualitative study"],"prefix":"10.1111","volume":"21","author":[{"given":"Erica","family":"di Martino","sequence":"first","affiliation":[{"name":"Faculty of Medicine and Health University of Leeds  Leeds UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6741-3078","authenticated-orcid":false,"given":"Elizabeth Andrea","family":"Nelson","sequence":"additional","affiliation":[{"name":"School of Health and Life Sciences Glasgow Caledonian University  Glasgow UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jane Elizabeth","family":"Nixon","sequence":"additional","affiliation":[{"name":"Faculty of Medicine and Health University of Leeds  Leeds UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David Alexander","family":"Russell","sequence":"additional","affiliation":[{"name":"Faculty of Medicine and Health University of Leeds  Leeds UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna Louise","family":"Goodman","sequence":"additional","affiliation":[{"name":"Centre for Clinical Infection and Diagnostics Research (CIDR), Guy's and St Thomas NHS Trust and King's College London MRC Clinical Trials Unit at UCL  London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sanjeev Rasiklal","family":"Mehta","sequence":"additional","affiliation":[{"name":"Ealing Hospital London North West University Healthcare NHS Trust  London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5294-4789","authenticated-orcid":false,"given":"Frances","family":"Game","sequence":"additional","affiliation":[{"name":"Research and Development Department University Hospitals of Derby and Burton NHS Foundation Trust  Derby UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,6,10]]},"reference":[{"doi-asserted-by":"publisher","key":"e_1_2_10_2_1","DOI":"10.1016\/S0140-6736(03)13169-8"},{"doi-asserted-by":"publisher","key":"e_1_2_10_3_1","DOI":"10.1002\/dmrr.2699"},{"key":"e_1_2_10_4_1","article-title":"Diabetic foot problems: prevention and management","author":"National Institute for Health and Care Excellence (NICE)","year":"2015","journal-title":"NICE Guideline [NG19]"},{"doi-asserted-by":"publisher","key":"e_1_2_10_5_1","DOI":"10.3389\/fcimb.2022.836699"},{"doi-asserted-by":"publisher","key":"e_1_2_10_6_1","DOI":"10.1186\/s12916\u2010014\u20100232\u20100"},{"doi-asserted-by":"publisher","key":"e_1_2_10_7_1","DOI":"10.1080\/08870440903194015"},{"volume-title":"Qualitative Research Practice: a Guide for Social Science Students and Researchers","year":"2003","author":"Ritchie J","key":"e_1_2_10_8_1"},{"doi-asserted-by":"publisher","key":"e_1_2_10_9_1","DOI":"10.1016\/j.dsx.2018.03.001"},{"issue":"6","key":"e_1_2_10_10_1","first-page":"1464","article-title":"Isolation and genetic analysis of multidrug resistant bacteria from diabetic foot ulcers","volume":"5","author":"Shahi SK","year":"2016","journal-title":"Front Microbiol"},{"doi-asserted-by":"publisher","key":"e_1_2_10_11_1","DOI":"10.1186\/s13104-019-4278-0"},{"doi-asserted-by":"publisher","key":"e_1_2_10_12_1","DOI":"10.2147\/IJGM.S278574"}],"container-title":["International Wound 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