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The primary objective was to analyse the effectiveness of the spray skin protectant \u2018non\u2010burning barrier film\u2019 in the prevention of radiodermatitis with moist desquamation in patients with the anal canal and rectal cancer followed in nursing consultations compared to a standardised moisturiser based on\n                    <jats:italic>Calendula officinalis<\/jats:italic>\n                    and\n                    <jats:italic>Aloe barbadensis<\/jats:italic>\n                    . Single\u2010blind randomised clinical trial. The study was performed in a hospital in Rio de Janeiro, Brazil, with 63 patients undergoing anal canal and rectal cancer treatment, randomised into one of the following two groups: an experimental group, which used a spray skin protectant and a control group, which used a moisturiser. Data were collected using an initial and subsequent evaluation form and were assessed using descriptive and inferential analyses. Participants who used the spray skin protectant had a lower chance of presenting radiodermatitis with moist desquamation and a longer time without this outcome when compared to the control group. The overall incidence of radiodermatitis was 100%, with 36.5% being severe. Furthermore, 17.5% of participants discontinued radiotherapy due to radiodermatitis. There were no differences between the groups regarding the severity of radiodermatitis and the number of patients who discontinued radiotherapy. The skin protectant was effective in preventing radiodermatitis with moist desquamation amongst patients with anal canal and rectal cancer.\n                  <\/jats:p>","DOI":"10.1111\/iwj.70030","type":"journal-article","created":{"date-parts":[[2024,8,22]],"date-time":"2024-08-22T16:56:51Z","timestamp":1724345811000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Spray skin protectant versus standard moisturiser in the prevention of radiodermatitis in patients with anal canal and rectal cancer: A randomised clinical trial"],"prefix":"10.1111","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1109-9363","authenticated-orcid":false,"given":"Fabiana Verdan","family":"Sim\u00f5es","sequence":"first","affiliation":[{"name":"Anna Nery School of Nursing Federal University of Rio de Janeiro  Rio de Janeiro Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3939-3545","authenticated-orcid":false,"given":"Thamiris","family":"da Silva e Silva","sequence":"additional","affiliation":[{"name":"Anna Nery School of Nursing Federal University of Rio de Janeiro  Rio de Janeiro Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8432-0735","authenticated-orcid":false,"given":"Aline Aniceto","family":"Pires","sequence":"additional","affiliation":[{"name":"Anna Nery School of Nursing Federal University of Rio de Janeiro  Rio de Janeiro Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caio Ribeiro Muzzi","family":"Fran\u00e7a","sequence":"additional","affiliation":[{"name":"Anna Nery School of Nursing Federal University of Rio de Janeiro  Rio de Janeiro Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8608-8784","authenticated-orcid":false,"given":"Nath\u00e1lia Sodr\u00e9","family":"Velasco","sequence":"additional","affiliation":[{"name":"Jos\u00e9 Alencar Gomes da Silva National Cancer Institute  Rio de Janeiro Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1777-155X","authenticated-orcid":false,"given":"Valdete Oliveira","family":"Santos","sequence":"additional","affiliation":[{"name":"Jos\u00e9 Alencar Gomes da Silva National Cancer Institute  Rio de Janeiro Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katia","family":"Moreira","sequence":"additional","affiliation":[{"name":"Jos\u00e9 Alencar Gomes da Silva National Cancer Institute  Rio de Janeiro Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4872-7252","authenticated-orcid":false,"given":"Marcelle Miranda","family":"da Silva","sequence":"additional","affiliation":[{"name":"Anna Nery School of Nursing Federal University of Rio de Janeiro  Rio de Janeiro Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8368-8343","authenticated-orcid":false,"given":"Marcos Ant\u00f4nio Gomes","family":"Brand\u00e3o","sequence":"additional","affiliation":[{"name":"Anna Nery School of Nursing Federal University of Rio de Janeiro  Rio de Janeiro Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7494-7457","authenticated-orcid":false,"given":"Beatriz Guitton Renaud Baptista","family":"de Oliveira","sequence":"additional","affiliation":[{"name":"Aurora of Afonso Costa School of Nursing Federal Fluminense University  Rio de Janeiro Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5211-9586","authenticated-orcid":false,"given":"Rafael Celestino","family":"da Silva","sequence":"additional","affiliation":[{"name":"Anna Nery School of Nursing Federal University of Rio de Janeiro  Rio de Janeiro Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,8,22]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1188\/20.ONF.654\u2010670"},{"issue":"12","key":"e_1_2_9_3_1","first-page":"885","article-title":"Radiation dermatitis: recognition, prevention, and management","volume":"31","author":"Leventhal J","year":"2017","journal-title":"Oncology (Williston Park)"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/0360\u20103016(95)00060\u2010C"},{"key":"e_1_2_9_5_1","unstructured":"US Department of Health and Human Services.Common Terminology Criteria for Adverse Events (CTCAE) version 5.0. 2017. 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