{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T19:38:59Z","timestamp":1786649939959,"version":"build-2736575974"},"reference-count":25,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2024,10,13]],"date-time":"2024-10-13T00:00:00Z","timestamp":1728777600000},"content-version":"vor","delay-in-days":12,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["International Wound Journal"],"published-print":{"date-parts":[[2024,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>This study evaluates the cost\u2010effectiveness of the geko device a neuromuscular electro\u2010stimulator technology with standard of care (SoC) versus SoC alone for venous leg ulcer (VLU) treatment, from the UK National Health Service (NHS) perspective over 12\u2009months. Research was conducted across NHS UK facilities, primarily within community services and outpatient leg ulcer clinics, encompassing a total of 51 patients. A partitioned survival model, based on a two\u2010arm randomised controlled trial, assessed wound healing rates using Kaplan\u2013Meier curves and parametric extrapolations over a 12\u2010month time horizon. Costs were derived from UK reference costs the British National Formulary, and the Personal Social Services Research Unit (2021\/22). The primary outcome measured was the incremental cost per quality\u2010adjusted life\u2010year gained. The geko device provides additional benefits by stimulating the lateral popliteal nerve, augmenting venous, arterial, and microvascular flow. The addition of the geko device to SoC significantly enhanced outcomes, increasing healing probability by 68% compared to SoC. This integration would result in a cost saving of \u00a3774.14 per patient when compared to the SoC alone across the NHS. Economic analyses indicate that integrating the geko device into SoC protocols would reduce the overall NHS expenditure on VLU wound management by as much as 15%. The approach also positively impacted health\u2010related quality of life. The geko\u2122 device when used adjunctively with SoC would be a cost\u2010effective method for managing chronic VLUs within the NHS, improving healing rates and offering economic benefits.<\/jats:p>","DOI":"10.1111\/iwj.70048","type":"journal-article","created":{"date-parts":[[2024,10,13]],"date-time":"2024-10-13T21:43:07Z","timestamp":1728855787000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Cost\u2010effectiveness analysis of the geko\u2122 device (an\n                    <scp>NMES<\/scp>\n                    technology) in managing venous leg ulcers in\n                    <scp>UK<\/scp>\n                    healthcare settings"],"prefix":"10.1111","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6113-3021","authenticated-orcid":false,"given":"Richard","family":"Tuson","sequence":"first","affiliation":[{"name":"Health Analytical Solutions Ltd  Macclesfield UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7412-6093","authenticated-orcid":false,"given":"Andrew","family":"Metry","sequence":"additional","affiliation":[{"name":"Health Analytical Solutions Ltd  Macclesfield UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0048-3279","authenticated-orcid":false,"given":"Keith","family":"Harding","sequence":"additional","affiliation":[{"name":"Health Analytical Solutions Ltd  Macclesfield UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,10,13]]},"reference":[{"key":"e_1_2_10_2_1","unstructured":"NHS Scotland.NHS INform Scotland. Accessed April 14 2023.https:\/\/www.nhsinform.scot\/illnesses\u2010and\u2010conditions\/skin\u2010hair\u2010and\u2010nails\/venous\u2010leg\u2010ulcer\/."},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/iwj.14107"},{"key":"e_1_2_10_4_1","unstructured":"NHS England.2020. Accessed April 13 2023.https:\/\/www.england.nhs.uk\/long\u2010read\/providing\u2010proactive\u2010care\u2010for\u2010people\u2010living\u2010in\u2010care\u2010homes\u2010enhanced\u2010health\u2010in\u2010care\u2010homes\u2010framework\/"},{"key":"e_1_2_10_5_1","unstructured":"NNWCS Programme.NWCSP National Wound Care Strategy Programme. Accessed November 20 2023.https:\/\/www.nationalwoundcarestrategy.net\/wp\u2010content\/uploads\/2023\/08\/NWCSP\u2010Leg\u2010Ulcer\u2010Recommendations\u20101.8.2023.pdf"},{"key":"e_1_2_10_6_1","unstructured":"NHS England.2023. 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Accessed August 22 2024.https:\/\/www.sheffield.ac.uk\/media\/34225\/download?attachment"},{"key":"e_1_2_10_16_1","unstructured":"NICE.National Institute for Health and Care Excellence.2023 \u2010 NICE health technology evaluations: the manual. Accessed April 12 2023.https:\/\/www.nice.org.uk\/process\/pmg36\/chapter\/committee-recommendations"},{"key":"e_1_2_10_17_1","unstructured":"NICE. UrgoStart for treating diabetic foot ulcers and leg ulcers. Accessed April 12 2023.https:\/\/www.nice.org.uk\/guidance\/mtg42"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.20692"},{"key":"e_1_2_10_19_1","volume-title":"National Schedule of NHS Costs 2021\/22. 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