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The \u2018Personalised and Multi\u2010dimensional Compression Assessment and Intervention\u2019 (PAMCAI) is a multidimensional decision aid, delivered by clinicians via an iPad application, designed to improve adherence. This study piloted the methodology and feasibility of PAMCAI's efficacy and cost\u2010effectiveness for evaluation in a larger randomised controlled trial (RCT). Using a two\u2010arm, single\u2010blinded pilot RCT with cost\u2010utility analysis, PAMCAI was compared with usual care in a tertiary hospital occupational therapy outpatient clinic. The primary outcome was adherence to wearing compression stockings, measured on a 4\u2010point scale. Twenty participants were randomised to receive PAMCAI (<jats:italic>n<\/jats:italic>\u2009=\u200910) or usual care (<jats:italic>n<\/jats:italic>\u2009=\u200910). Recruitment and pilot methodology appear feasible for use in a larger study. Compression stocking adherence was greater with PAMCAI compared to usual care (<jats:italic>p<\/jats:italic>\u2009=\u20090.002) and PAMCAI is likely cost\u2010effective, with an incremental cost\u2010effectiveness ratio of $3379.36 per quality\u2010adjusted life year (QALY) gained. Resolution of identified barriers to stocking adherence was positively associated with improvements in patient adherence. These findings support further investigation of PAMCAI in a larger RCT and its potential to improve patient adherence and the cost\u2010effectiveness of compression therapy for venous leg ulcer prevention.<\/jats:p>","DOI":"10.1111\/iwj.70244","type":"journal-article","created":{"date-parts":[[2025,4,16]],"date-time":"2025-04-16T01:38:06Z","timestamp":1744767486000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Adherence to Compression Stockings for Venous Leg Ulcer Prevention: A Pilot Randomised Controlled Trial and Health Economic Analysis, Evaluating a New Multidimensional Tool (<scp>PAMCAI<\/scp>)"],"prefix":"10.1111","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9261-6395","authenticated-orcid":false,"given":"Laila","family":"Bar","sequence":"first","affiliation":[{"name":"Faculty of Health Science and Medicine Bond University  Gold Coast Queensland Australia"},{"name":"Gold Coast Hospital and Health Service  Gold Coast Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2613-4114","authenticated-orcid":false,"given":"Susan","family":"Brandis","sequence":"additional","affiliation":[{"name":"Faculty of Health Science and Medicine Bond University  Gold Coast Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2100-4898","authenticated-orcid":false,"given":"Rachel","family":"Wenke","sequence":"additional","affiliation":[{"name":"Faculty of Health Science and Medicine Bond University  Gold Coast Queensland Australia"},{"name":"Gold Coast Hospital and Health Service  Gold Coast Queensland Australia"},{"name":"School of Health Sciences and Social Work Griffith University  Gold Coast Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8884-8596","authenticated-orcid":false,"given":"Darryn","family":"Marks","sequence":"additional","affiliation":[{"name":"Faculty of Health Science and Medicine Bond University  Gold Coast Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,4,15]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.12968\/jowc.2020.29.3.141"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1177\/1358863X211028298"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/iwj.14272"},{"issue":"5","key":"e_1_2_11_5_1","first-page":"331","article-title":"Venous Leg Ulcer Management in General Practice\u2010Practice Nurses and Evidence\u2010Based Guidelines","volume":"41","author":"Weller C.","year":"2012","journal-title":"Australian Family Physician"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12913\u2010018\u20103234\u20103"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/iwj.14309"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1742\u2010481X.2012.01108.x"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/jan.14611"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.avsg.2007.07.014"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1742\u2010481X.2009.00634.x"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/iwj.13000"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365\u20102702.2006.01863.x"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.2147\/PPA.S323766"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.2147\/PPA.S390123"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.i5239"},{"key":"e_1_2_11_17_1","volume-title":"Concession and Health Cards","author":"Australian Government Department of Social Services","year":"2024"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1177\/0268355518762824"},{"key":"e_1_2_11_19_1","volume-title":"Queensland Health Careers. 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