{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,25]],"date-time":"2025-11-25T00:12:04Z","timestamp":1764029524907,"version":"3.45.0"},"reference-count":69,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T00:00:00Z","timestamp":1762992000000},"content-version":"vor","delay-in-days":12,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["International Wound Journal"],"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>The healthcare landscape in South Africa is challenging with a complex patient population and a stressed healthcare system. Negative pressure therapy\u2010based systems such as negative pressure wound therapy with instillation and dwell (NPWTi\u2010d) and closed incision negative pressure therapy (ciNPT) can help manage wounds or incisions. However, guidelines for South Africa\u2010specific use are limited. An in\u2010person meeting was held with 10 experts to develop South Africa\u2010specific therapy use recommendations for NPWTi\u2010d and ciNPT. Panel members recommended NPWTi\u2010d use for wounds in need of cleansing. Normal saline and a 10\u2010min dwell time were recommended with the caveat that the instillation solutions and dwell times can be changed based on the wound bed condition and the features of the instillation solution. A negative pressure cycle of 2\u20133\u2009h and a negative pressure of \u2212125\u2009mmHg were also recommended for NPWTi\u2010d. In patients, incisions, and surgical procedures at high risk of developing surgical site complications, ciNPT use was recommended. These general recommendations serve as a framework for NPWTi\u2010d and\/or ciNPT use in South Africa and should be updated as more region\u2010specific evidence becomes available.<\/jats:p>","DOI":"10.1111\/iwj.70790","type":"journal-article","created":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T13:06:21Z","timestamp":1763039181000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Negative Pressure Wound Therapy With Instillation and Closed Incision Negative Pressure Therapy Use in South Africa: Expert Panel Recommendations"],"prefix":"10.1111","volume":"22","author":[{"given":"Ethel","family":"Andrews","sequence":"first","affiliation":[{"name":"Nursing Education University of Witwatersrand  Johannesburg South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emmanuel","family":"Arko\u2010Cobbah","sequence":"additional","affiliation":[{"name":"Surgery, Mediclinic Bloemfontein  Bloemfontein South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0947-0159","authenticated-orcid":false,"given":"F\u00e9b\u00e9","family":"Bruwer","sequence":"additional","affiliation":[{"name":"Advanced Wound Care Life Roseacres Hospital  Germiston South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saadia","family":"Laher","sequence":"additional","affiliation":[{"name":"Plastic and Reconstructive Surgery Netcare Alberton Hospital  Alberton South Africa"},{"name":"Plastic and Reconstructive Surgery Midvaal Hospital  Johannesburg South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sanesh","family":"Miseer","sequence":"additional","affiliation":[{"name":"Orthopaedics Tygerberg Academic Hospital  Cape Town South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maeyane S.","family":"Moeng","sequence":"additional","affiliation":[{"name":"Trauma Surgery University of Witwatersrand  Johannesburg South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anati","family":"Ngcakani","sequence":"additional","affiliation":[{"name":"Orthopaedics Edenvale General Hospital  Edenvale South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Devan","family":"Scott","sequence":"additional","affiliation":[{"name":"Cardiothoracic Surgery Life Anncron Hospital  Klerksdorp South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sul\u00e9man","family":"Vadia","sequence":"additional","affiliation":[{"name":"Plastic, Reconstructive, and Cosmetic Surgery Netcare Milpark and Rosebank Hospital  Johannesburg South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-6961-968X","authenticated-orcid":false,"given":"Sadhana","family":"Trivedi","sequence":"additional","affiliation":[{"name":"Medical Surgical Solventum  Dublin Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,11,13]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.diabres.2021.109119"},{"key":"e_1_2_10_3_1","unstructured":"New HIV Survey Highlights Progress and Ongoing Disparities in South Africa's HIV Epidemic. 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