{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T07:49:13Z","timestamp":1782200953487,"version":"3.54.5"},"reference-count":30,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2026,6,12]],"date-time":"2026-06-12T00:00:00Z","timestamp":1781222400000},"content-version":"vor","delay-in-days":11,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["International Wound Journal"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Crohn's disease (CD) is primarily characterised by chronic gastrointestinal inflammation; however, its systemic nature frequently leads to musculoskeletal complications. Among these, clinically significant foot pathologies can impair mobility and negatively impact patients' overall quality of life. Despite their relevance, the specific influence of podiatric manifestations on health\u2010related quality of life in individuals with CD remains insufficiently explored, underscoring a critical gap in current disease management. The aim of this study was to assess the extent to which foot\u2010related health issues affect the quality of life in people living with CD compared with a healthy population. This multicenter observational case\u2013control study was conducted across five provinces in southern Spain\u2014M\u00e1laga, Granada, Ja\u00e9n, Sevilla, and C\u00e1diz\u2014between January 2024 and February 2025. The study included 110 participants, evenly divided between individuals diagnosed with CD (\n                    <jats:italic>n<\/jats:italic>\n                    \u2009=\u200955) and healthy controls (\n                    <jats:italic>n<\/jats:italic>\n                    \u2009=\u200955), matched for age, sex, and body mass index. All participants completed the validated Spanish version of the Foot Health Status Questionnaire (SFHSQ), which assesses four foot\u2010specific domains and four general health domains. Due to the non\u2010normal distribution of the data, non\u2010parametric statistical methods were applied, with the Mann\u2013Whitney\n                    <jats:italic>U<\/jats:italic>\n                    test used to evaluate differences between groups. Participants with CD exhibited significantly lower scores across all domains of the SFHSQ, with the exception of the Footwear domain, which showed no statistically significant difference (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.406). Compared with healthy controls, individuals in the CD group reported greater impairments in foot pain, foot function, general foot health, and in broader health\u2010related domains including general health, physical activity, and social capacity (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.01 for all). CD significantly compromises foot\u2010related QoL. These results highlight the need to include podiatric evaluations as part of comprehensive, multidisciplinary care approaches aimed at enhancing mobility, functional capacity, and general well\u2010being in affected individuals.\n                  <\/jats:p>","DOI":"10.1111\/iwj.70798","type":"journal-article","created":{"date-parts":[[2026,6,12]],"date-time":"2026-06-12T08:10:37Z","timestamp":1781251837000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Assessing the Impact of Crohn's Disease on Foot Health\u2010Related Quality of Life: A Case\u2013Control Study"],"prefix":"10.1111","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-6734-4328","authenticated-orcid":false,"given":"Juan Manuel","family":"Escudero\u2010Prados","sequence":"first","affiliation":[{"name":"Research, Health and Podiatry Group, Department of Health Sciences, Faculty of Nursing and Podiatry, Industrial Campus of Ferrol Universidade da Coru\u00f1a  Ferrol Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4660-5596","authenticated-orcid":false,"given":"Antonio","family":"Cort\u00e9s\u2010Rodr\u00edguez","sequence":"additional","affiliation":[{"name":"Research, Health and Podiatry Group, Department of Health Sciences, Faculty of Nursing and Podiatry, Industrial Campus of Ferrol Universidade da Coru\u00f1a  Ferrol Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0445-8399","authenticated-orcid":false,"given":"Ana J\u00falia","family":"Monteiro","sequence":"additional","affiliation":[{"name":"Physiotherapy Department Escola Superior de Sa\u00fade da Cruz Vermelha Portuguesa \u2010 Lisboa  Lisbon Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7588-2069","authenticated-orcid":false,"given":"Marta E.","family":"Losa\u2010Iglesias","sequence":"additional","affiliation":[{"name":"Faculty of Health Sciences Universidad Rey Juan Carlos  Alcorc\u00f3n Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9053-7730","authenticated-orcid":false,"given":"Juan","family":"G\u00f3mez\u2010Salgado","sequence":"additional","affiliation":[{"name":"Department of Sociology, Social Work and Public Health, Faculty of Labour Sciences Universidad de Huelva  Huelva Spain"},{"name":"Safety and Health Postgraduate Programme Universidad Esp\u00edritu Santo  Guayaquil Ecuador"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1568-7602","authenticated-orcid":false,"given":"Ricardo","family":"Becerro\u2010de\u2010Bengoa\u2010Vallejo","sequence":"additional","affiliation":[{"name":"Faculty of Nursing, Physiotherapy and Podiatry Universidad Complutense de Madrid  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6248-9188","authenticated-orcid":false,"given":"Miguel A.","family":"Saavedra\u2010Garc\u00eda","sequence":"additional","affiliation":[{"name":"Grupo de Investigaci\u00f3n en Ciencias del Deporte (INCIDE), Department of Physical Education and Sport Unversidade da Coru\u00f1a  A Coru\u00f1a Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9818-6290","authenticated-orcid":false,"given":"Daniel","family":"L\u00f3pez\u2010L\u00f3pez","sequence":"additional","affiliation":[{"name":"Research, Health and Podiatry Group, Department of Health Sciences, Faculty of Nursing and Podiatry, Industrial Campus of Ferrol Universidade da Coru\u00f1a  Ferrol Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8634-7114","authenticated-orcid":false,"given":"Ana M.","family":"Jim\u00e9nez\u2010Cebri\u00e1n","sequence":"additional","affiliation":[{"name":"Nursing and Podiatry Department University of M\u00e1laga  M\u00e1laga Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,6,12]]},"reference":[{"issue":"6","key":"e_1_2_12_2_1","first-page":"549","article-title":"Crohn's Disease: An Update","volume":"23","author":"Cockburn E.","year":"2023","journal-title":"Clinical Medicine, Journal of the Royal College of Physicians of London"},{"key":"e_1_2_12_3_1","first-page":"26","article-title":"Crohn's Disease","volume":"151","author":"Ballester Ferr\u00e9 M. P.","year":"2018","journal-title":"Medicina Cl\u00ednica"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41575-020-00360-x"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41572-020-0193-x"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(16)31711-1"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mayocp.2018.09.013"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12325-023-02473-6"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/ibd\/izad061"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/MIB.0000000000000392"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1080\/17474124.2019.1574569"},{"issue":"11","key":"e_1_2_12_12_1","first-page":"757","article-title":"Evolution of the Incidence of Inflammatory Bowel Disease in Southern Spain","volume":"109","author":"Chaaro\u2010Benallal D.","year":"2017","journal-title":"Revista Espa\u00f1ola de Enfermedades Digestivas"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rmclc.2019.06.003"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm10132885"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.crohns.2013.01.010"},{"key":"e_1_2_12_16_1","unstructured":"D. G.Moriarty M. M.Zack R.Kobau M. M.Zack\u2010MZack andR.Kobau \u2010RKobau Health and Quality of Life Outcomes. The Centers for Disease Control and Prevention's Healthy Days Measures\u2010Population Tracking of Perceived Physical and Mental Health Over Time Background and Development of the Measures(2003) https:\/\/www.cdc.gov\/hrqol\/methods.htm."},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.2478\/rir-2022-0012"},{"key":"e_1_2_12_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijsu.2014.07.014"},{"key":"e_1_2_12_19_1","doi-asserted-by":"publisher","DOI":"10.7547\/87507315-88-9-419"},{"key":"e_1_2_12_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11136-012-0287-3"},{"key":"e_1_2_12_21_1","doi-asserted-by":"publisher","DOI":"10.1177\/107110070202300611"},{"key":"e_1_2_12_22_1","doi-asserted-by":"publisher","DOI":"10.4067\/S1726\u2010569X2000000200010"},{"key":"e_1_2_12_23_1","doi-asserted-by":"publisher","DOI":"10.3389\/ijph.2023.1605593"},{"key":"e_1_2_12_24_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2024.1355803"},{"key":"e_1_2_12_25_1","doi-asserted-by":"publisher","DOI":"10.1093\/ecco-jcc\/jjv213"},{"key":"e_1_2_12_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fas.2017.10.016"},{"key":"e_1_2_12_27_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00296-024-05710-5"},{"key":"e_1_2_12_28_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2021.730273"},{"key":"e_1_2_12_29_1","article-title":"Diagnosis and Management of Haemophilia","volume":"344","author":"Fijnvandraat K.","year":"2012","journal-title":"BMJ (Clinical Research Edition)"},{"key":"e_1_2_12_30_1","doi-asserted-by":"publisher","DOI":"10.1111\/iwj.13844"},{"key":"e_1_2_12_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0016-5085(76)80163-1"}],"container-title":["International Wound Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/iwj.70798","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/iwj.70798","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/iwj.70798","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T07:21:05Z","timestamp":1782199265000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/iwj.70798"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6]]},"references-count":30,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2026,6]]}},"alternative-id":["10.1111\/iwj.70798"],"URL":"https:\/\/doi.org\/10.1111\/iwj.70798","archive":["Portico"],"relation":{},"ISSN":["1742-4801","1742-481X"],"issn-type":[{"value":"1742-4801","type":"print"},{"value":"1742-481X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,6]]},"assertion":[{"value":"2025-07-22","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-11-15","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-06-12","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70798"}}