{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T00:17:00Z","timestamp":1773015420236,"version":"3.50.1"},"reference-count":37,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T00:00:00Z","timestamp":1768348800000},"content-version":"vor","delay-in-days":13,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100017847","name":"Medline Industries","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100017847","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["International Wound Journal"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    A comprehensive skincare regimen involves cleansing, moisturising, and using skin barrier protectants. Cyanoacrylate\u2010based protectants safeguard vulnerable skin from damage caused by moisture, friction, and shear. This research involved two ex\u00a0vivo and two clinical studies comparing the wear duration and wash\u2010off resistance of a 100% cyanoacrylate and a solvent\u2010cyanoacrylate mixture. Effectiveness was assessed using an ex\u00a0vivo porcine skin model simulating urinary incontinence, evaluated with Lucifer yellow dye penetration and Corneometry, and a clinical model using Corneometry. Two single\u2010blind clinical studies measured skin surface electrical capacitance in healthy volunteers. Study 1 (\n                    <jats:italic>n<\/jats:italic>\n                    \u2009=\u200942) evaluated the wear duration over 8\u2009days, while Study 2 (\n                    <jats:italic>n<\/jats:italic>\n                    \u2009=\u200952) examined wash\u2010off resistance after nine washes with various cleansers. Ex\u00a0vivo results showed that both products were effective under repeated moisture and abrasion conditions, with the 100% cyanoacrylate outperforming the solvent\u2010cyanoacrylate mixture. In clinical studies, both products maintained barrier protection throughout Study 1 (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.007) and none of the cleansers significantly degraded either product in Study 2. In conclusion, the 100% cyanoacrylate provided superior protection compared to the solvent\u2010cyanoacrylate mixture. Both products demonstrated comparable wear duration and wash\u2010off resistance in clinical studies, but the 100% cyanoacrylate was more effective in ex\u00a0vivo testing under harsh conditions.\n                  <\/jats:p>","DOI":"10.1111\/iwj.70807","type":"journal-article","created":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T13:23:46Z","timestamp":1768397026000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Comparative Analyses of Cyanoacrylates for Barrier Protection and Incontinence\u2010Related Wash\u2010Off Resistance"],"prefix":"10.1111","volume":"23","author":[{"given":"Madhumita A.","family":"Pradhan","sequence":"first","affiliation":[{"name":"Medline Industries, LP  Northfield Illinois USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lisa M.","family":"Nicholson","sequence":"additional","affiliation":[{"name":"Medline Industries, LP  Northfield Illinois USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lauren S.","family":"Coles","sequence":"additional","affiliation":[{"name":"Medline Industries, LP  Northfield Illinois USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jessica J.","family":"Campbell","sequence":"additional","affiliation":[{"name":"Medline Industries, LP  Northfield Illinois USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brenda J.","family":"Curtis","sequence":"additional","affiliation":[{"name":"Medline Industries, LP  Northfield Illinois USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,1,14]]},"reference":[{"key":"e_1_2_15_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.ASW.0000525627.54569.da"},{"key":"e_1_2_15_3_1","doi-asserted-by":"publisher","DOI":"10.3109\/09546639709160948"},{"key":"e_1_2_15_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/ddg.14388"},{"key":"e_1_2_15_5_1","doi-asserted-by":"publisher","DOI":"10.12968\/bjcn.2020.25.Sup3.S12"},{"key":"e_1_2_15_6_1","doi-asserted-by":"publisher","DOI":"10.12968\/bjon.2012.21.9.517"},{"key":"e_1_2_15_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtv.2016.02.004"},{"key":"e_1_2_15_8_1","doi-asserted-by":"publisher","DOI":"10.12968\/bjon.2020.29.12.S30"},{"key":"e_1_2_15_9_1","doi-asserted-by":"publisher","DOI":"10.12968\/bjcn.2013.18.1.6"},{"key":"e_1_2_15_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.ASW.0000521048.64537.6e"},{"key":"e_1_2_15_11_1","doi-asserted-by":"publisher","DOI":"10.12968\/bjon.2014.23.Sup20.S22"},{"key":"e_1_2_15_12_1","doi-asserted-by":"publisher","DOI":"10.33235\/wpr.32.1.25\u201033"},{"key":"e_1_2_15_13_1","doi-asserted-by":"publisher","DOI":"10.7748\/ns.2019.e11314"},{"key":"e_1_2_15_14_1","doi-asserted-by":"publisher","DOI":"10.12968\/bjon.2021.30.15.S40"},{"key":"e_1_2_15_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcws.2011.02.003"},{"key":"e_1_2_15_16_1","doi-asserted-by":"publisher","DOI":"10.12968\/jowc.2019.28.2.110"},{"key":"e_1_2_15_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0846.2011.00573.x"},{"key":"e_1_2_15_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/srt.13292"},{"key":"e_1_2_15_19_1","doi-asserted-by":"publisher","DOI":"10.5021\/ad.23.103"},{"key":"e_1_2_15_20_1","doi-asserted-by":"publisher","DOI":"10.1177\/41.6.8315281"},{"key":"e_1_2_15_21_1","doi-asserted-by":"publisher","DOI":"10.1007\/978\u20101\u201061779\u2010191\u20108_4"},{"key":"e_1_2_15_22_1","doi-asserted-by":"publisher","DOI":"10.12968\/jowc.2020.29.1.18"},{"key":"e_1_2_15_23_1","doi-asserted-by":"publisher","DOI":"10.1097\/WON.0000000000000307"},{"key":"e_1_2_15_24_1","doi-asserted-by":"publisher","DOI":"10.1097\/WON.0000000000001027"},{"key":"e_1_2_15_25_1","doi-asserted-by":"publisher","DOI":"10.25270\/wnds\/22026"},{"key":"e_1_2_15_26_1","doi-asserted-by":"publisher","DOI":"10.12968\/bjcn.2022.27.6.280"},{"issue":"2","key":"e_1_2_15_27_1","first-page":"99","article-title":"Comparison of a Cyanoacrylate Liquid Skin Protectant to Skin Closure Strips for the Treatment of Injury\u2010Related Type I Skin Tears in Elderly Patients","volume":"23","author":"Hill R. 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