{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T05:17:34Z","timestamp":1773033454567,"version":"3.50.1"},"reference-count":41,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2026,2,9]],"date-time":"2026-02-09T00:00:00Z","timestamp":1770595200000},"content-version":"vor","delay-in-days":8,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100000632","name":"Healthcare Infection Society","doi-asserted-by":"publisher","award":["MRG\u20102022\u2010003"],"award-info":[{"award-number":["MRG\u20102022\u2010003"]}],"id":[{"id":"10.13039\/501100000632","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["International Wound Journal"],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Surgical site infections (SSI) in vascular surgery have a huge impact on patients\u2019 morbidity and mortality and healthcare systems worldwide. Dialkylcarbamoylchoride (DACC) is a synthetically produced material that can irreversibly bind and inactivate bacteria that exhibit cell\u2010surface hydrophobicity (CSH). The DACC in the Reduction of Surgical Site Infection (DRESSINg) trial is a multicentre randomised controlled trial which aims to assess the effectiveness of DACC\u2010coated post\u2010operative dressings in the prevention of SSI in vascular surgery. Seven hundred and eighteen participants undergoing clean or clean\u2010contaminated lower limb vascular surgery will be randomised in a 1:1 ratio to either DACC\u2010coated dressings or standard dressings for their postoperative wounds. The primary outcome is the incidence of SSI defined by the Centers for Disease Control and Prevention (CDC) criteria or total ASEPSIS score of 21 or more within 30\u2009days of surgery. The secondary outcomes include satisfactory wound healing with a total ASEPSIS score of 10 or less, quality of life pre and post surgery, Bluebelle wound healing scores, resource use and financial (\u00a3), and environmental (KgCO2e) cost analyses. This multicentre randomised controlled trial will provide level 1 evidence on the effectiveness of preventing SSI in lower limb vascular surgery.<\/jats:p>","DOI":"10.1111\/iwj.70818","type":"journal-article","created":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T01:59:26Z","timestamp":1770688766000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Assessing the Clinical and Cost Effectiveness of Dialkylcarbamoylchloride (\n                    <scp>DACC<\/scp>\n                    ) Coated Post\u2010Operative Dressings Versus Standard Care in the Prevention of Surgical Site Infection in Clean or Clean\u2010Contaminated, Vascular Surgery (\n                    <scp>DRESSINg<\/scp>\n                    Trial): Study Protocol for a Multicentre Randomised Controlled Trial"],"prefix":"10.1111","volume":"23","author":[{"given":"Arthur Jun Ming","family":"Lim","sequence":"first","affiliation":[{"name":"Academic Vascular Surgical Unit Hull York Medical School  Hull UK"},{"name":"Centre for Clinical Sciences Hull York Medical School  Hull UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ross","family":"Lathan","sequence":"additional","affiliation":[{"name":"Academic Vascular Surgical Unit Hull York Medical School  Hull UK"},{"name":"Centre for Clinical Sciences Hull York Medical School  Hull UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joshua","family":"Totty","sequence":"additional","affiliation":[{"name":"Academic Vascular Surgical Unit Hull York Medical School  Hull UK"},{"name":"Centre for Clinical Sciences Hull York Medical School  Hull UK"},{"name":"Department of Plastic and Reconstructive Surgery Hull University Teaching Hospitals NHS Trust  Hull UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Louise","family":"Hitchman","sequence":"additional","affiliation":[{"name":"Academic Vascular Surgical Unit Hull York Medical School  Hull UK"},{"name":"Centre for Clinical Sciences Hull York Medical School  Hull UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph","family":"Cutteridge","sequence":"additional","affiliation":[{"name":"Academic Vascular Surgical Unit Hull York Medical School  Hull UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kate","family":"Adams","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases Hull University Teaching Hospitals NHS Trust  Hull UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Phillipa","family":"Burns","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases Hull University Teaching Hospitals NHS Trust  Hull UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Judith","family":"Long","sequence":"additional","affiliation":[{"name":"Academic Vascular Surgical Unit Hull York Medical School  Hull UK"},{"name":"Centre for Clinical Sciences Hull York Medical School  Hull UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3627-7218","authenticated-orcid":false,"given":"Chao","family":"Huang","sequence":"additional","affiliation":[{"name":"Centre for Clinical Sciences Hull York Medical School  Hull UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leanne","family":"Cox","sequence":"additional","affiliation":[{"name":"Academic Vascular Surgical Unit Hull York Medical School  Hull UK"},{"name":"Centre for Clinical Sciences Hull York Medical School  Hull UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel","family":"Carradice","sequence":"additional","affiliation":[{"name":"Academic Vascular Surgical Unit Hull York Medical School  Hull UK"},{"name":"Centre for Clinical Sciences Hull York Medical School  Hull UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"George","family":"Smith","sequence":"additional","affiliation":[{"name":"Academic Vascular Surgical Unit Hull York Medical School  Hull UK"},{"name":"Centre for Clinical Sciences Hull York Medical School  Hull UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ian","family":"Chetter","sequence":"additional","affiliation":[{"name":"Academic Vascular Surgical Unit Hull York Medical School  Hull UK"},{"name":"Centre for Clinical Sciences Hull York Medical School  Hull UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,2,9]]},"reference":[{"issue":"4","key":"e_1_2_10_2_1","first-page":"110","article-title":"Research Priorities for Vascular Wounds: Results of the Vascular Society GBI\/James Lind Alliance Priority Setting Process","volume":"1","author":"Long J.","year":"2022","journal-title":"Journal of Vascular Societies Great Britain and Ireland"},{"key":"e_1_2_10_3_1","volume-title":"Surgical Site Infections: Prevention and Treatment. 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