{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T05:17:50Z","timestamp":1773033470231,"version":"3.50.1"},"reference-count":29,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T00:00:00Z","timestamp":1770768000000},"content-version":"vor","delay-in-days":10,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2022YFC2504302"],"award-info":[{"award-number":["2022YFC2504302"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005089","name":"Natural Science Foundation of Beijing Municipality","doi-asserted-by":"publisher","award":["L234015"],"award-info":[{"award-number":["L234015"]}],"id":[{"id":"10.13039\/501100005089","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["International Wound Journal"],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    This retrospective study aimed to evaluate the clinical efficacy of double flap tibial transverse transport (dTTT) in the treatment of Wagner grade 3\u20134 diabetic foot ulcers (DFUs) and to assess its impact on peripheral nerve function in the affected limb. A total of 25 patients with DFUs who underwent dTTT at our institution were included. Baseline data were collected, and patients were systematically followed at 1, 3, 6 and 12\u2009months postoperatively. Primary outcome measures included wound healing status, postoperative complications, microcirculatory indicators and nerve conduction parameters. All bone transport sites healed successfully, with no major complications observed except for one patient who died from COVID\u201019. At 12\u2009months postoperatively, significant improvements were noted in foot skin temperature, transcutaneous oxygen partial pressure and the ankle\u2010brachial index (all\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.001). Additionally, motor nerve conduction velocities of the posterior tibial and common peroneal nerves increased significantly (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.001), and corresponding compound muscle action potential amplitudes rose to 4.91\u2009\u00b1\u20090.14\u2009mV and 4.68\u2009\u00b1\u20090.29\u2009mV, respectively (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.001). These findings suggest that dTTT not only facilitates wound healing by improving local microcirculation but also enhances peripheral nerve function, offering a promising therapeutic approach for improving long\u2010term outcomes and quality of life in patients with advanced DFUs.\n                  <\/jats:p>","DOI":"10.1111\/iwj.70848","type":"journal-article","created":{"date-parts":[[2026,2,12]],"date-time":"2026-02-12T06:10:47Z","timestamp":1770876647000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Double Flap Tibial Transverse Transport Improves Microcirculation and Peripheral Nerve Function in Severe Diabetic Foot Ulcers"],"prefix":"10.1111","volume":"23","author":[{"given":"Yusong","family":"Yuan","sequence":"first","affiliation":[{"name":"Diabetic Foot Treatment Center PLA Army 82nd Group Army Hospital  Baoding China"},{"name":"Department of Trauma and Orthopaedics China\u2013Japan Friendship Hospital  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Longgang","family":"Liu","sequence":"additional","affiliation":[{"name":"Diabetic Foot Treatment Center PLA Army 82nd Group Army Hospital  Baoding China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hailing","family":"Yue","sequence":"additional","affiliation":[{"name":"Diabetic Foot Treatment Center PLA Army 82nd Group Army Hospital  Baoding China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chenyang","family":"Wang","sequence":"additional","affiliation":[{"name":"Diabetic Foot Treatment Center PLA Army 82nd Group Army Hospital  Baoding China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoran","family":"Zhang","sequence":"additional","affiliation":[{"name":"Diabetic Foot Treatment Center PLA Army 82nd Group Army Hospital  Baoding 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China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hailin","family":"Xu","sequence":"additional","affiliation":[{"name":"Diabetic Foot Treatment Center PLA Army 82nd Group Army Hospital  Baoding China"},{"name":"Department of Trauma and Orthopaedics, Peking University People's Hospital Peking University  Beijing China"},{"name":"Foot and Ankle Surgery Center Peking University People's Hospital  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,2,11]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2023.17191"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2023.10578"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.2147\/CCID.S333660"},{"issue":"5","key":"e_1_2_10_5_1","article-title":"Diabetic Foot Ulcers: Pathophysiology, Immune Dysregulation, and Emerging Therapeutic Strategies","volume":"13","author":"Dawi 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