{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T21:57:27Z","timestamp":1791496647231,"version":"4.3.4"},"reference-count":39,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2026,2,25]],"date-time":"2026-02-25T00:00:00Z","timestamp":1771977600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,2,25]],"date-time":"2026-02-25T00:00:00Z","timestamp":1771977600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001793","name":"Queensland University of Technology","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001793","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["2034266"],"award-info":[{"award-number":["2034266"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["International Wound Journal"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Cognitive impairment is associated with people with diabetes\u2010related foot ulcers (DFU). However, it is unclear if cognitive impairment is associated with the ulcer itself or other co\u2010existing diabetes\u2010related complications such as peripheral neuropathy. We aimed to investigate cognition in people with diabetes\u2010related peripheral neuropathy and compare those with DFUs to those without DFUs. In this age\u2010 and sex\u2010matched, multicentre, case\u2010control, observational study of 89 participants with Type 2 diabetes and peripheral neuropathy, we compared 49 participants with DFUs (cases) to 40 without DFUs (controls). Global cognition scores were assessed using the Montreal Cognitive Assessment tool. Participants with DFUs had similar characteristics to those without DFUs (all,\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&gt;\u20090.05), except for lower body mass index (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.028). Participants with active DFUs had significantly lower global cognition scores compared to those without DFUs (median [IQR] 24.0 [21.0\u201325.0], 26.0 [24.0\u201328.0];\n                    <jats:italic>p\u2009&lt;<\/jats:italic>\n                    \u20090\n                    <jats:italic>.<\/jats:italic>\n                    001). After adjusting for other diabetes\u2010related complications, lower global cognition was independently associated with a DFU, peripheral artery disease, lower physical activity and no family history of diabetes (all,\n                    <jats:italic>p<\/jats:italic>\n                    \u2009\u2264\u20090.019). People with DFUs had lower cognitive scores than those without DFUs, suggesting that the DFU itself is independently associated with cognitive impairment. Future studies should explore causal pathways and targeted management strategies.\n                  <\/jats:p>","DOI":"10.1111\/iwj.70867","type":"journal-article","created":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T11:17:23Z","timestamp":1772968643000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Cognitive Impairment in People With Diabetes\u2010Related Foot Ulcers: A Multicentre, Case\u2013Control, Observational Study"],"prefix":"10.1111","volume":"23","author":[{"given":"Nimantha","family":"Karunathilaka","sequence":"first","affiliation":[{"name":"Centre for Healthcare Transformation, Queensland University of Technology  Brisbane Queensland Australia"},{"name":"School of Nursing, Queensland University of Technology  Brisbane Queensland Australia"},{"name":"Department of Nursing and Midwifery Faculty of Allied Health Sciences, General Sir John Kotelawala Defence University  Ratmalana Sri Lanka"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter Anthony","family":"Lazzarini","sequence":"additional","affiliation":[{"name":"Centre for Healthcare Transformation, Queensland University of Technology  Brisbane Queensland Australia"},{"name":"School of Public Health and Social Work, Queensland University of Technology  Brisbane Queensland Australia"},{"name":"Allied Health Research Collaborative, the Prince Charles Hospital  Brisbane Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Margaret","family":"MacAndrew","sequence":"additional","affiliation":[{"name":"Centre for Healthcare Transformation, Queensland University of Technology  Brisbane Queensland Australia"},{"name":"School of Nursing, Queensland University of Technology  Brisbane Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathleen","family":"Finlayson","sequence":"additional","affiliation":[{"name":"Centre for Healthcare Transformation, Queensland University of Technology  Brisbane Queensland Australia"},{"name":"School of Nursing, Queensland University of Technology  Brisbane Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3834-205X","authenticated-orcid":false,"given":"Christina","family":"Parker","sequence":"additional","affiliation":[{"name":"Centre for Healthcare Transformation, Queensland University of Technology  Brisbane Queensland Australia"},{"name":"School of Nursing, Queensland University of Technology  Brisbane Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,2,25]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.2337\/dci22-0043"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/dmrr.3747"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00125-022-05845-9"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/dmrr.3268"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/dmrr.3266"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2019.05.044"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00125-019-04977-9"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-8587(20)30118-2"},{"issue":"1","key":"e_1_2_11_10_1","first-page":"S86","article-title":"5. Facilitating Positive Health Behaviors and Well\u2010Being to Improve Health Outcomes: Standards of Care in Diabetes\u20142025","volume":"48","author":"American Diabetes Association Professional Practice Committee","year":"2024","journal-title":"Diabetes Care"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12529-024-10274-6"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1080\/14737175.2022.2048649"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12902-024-01774-3"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.diabet.2017.12.005"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc15-2838"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdiacomp.2014.07.005"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12933-016-0483-5"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1177\/1534734619862085"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40200-023-01381-4"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1177\/107110070502600203"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm10132808"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.33235\/wpr.31.4.197-203"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.1186\/1757-1146-7-7"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc20-3120"},{"key":"e_1_2_11_25_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1525-1497.2001.016009606.x"},{"key":"e_1_2_11_26_1","doi-asserted-by":"publisher","DOI":"10.1249\/00005768-199305000-00016"},{"key":"e_1_2_11_27_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005768-200106000-00015"},{"key":"e_1_2_11_28_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.2005.53221.x"},{"key":"e_1_2_11_29_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc25-S013"},{"key":"e_1_2_11_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jocn.2017.08.039"},{"key":"e_1_2_11_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.trci.2019.06.005"},{"key":"e_1_2_11_32_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00592-020-01648-9"},{"key":"e_1_2_11_33_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000000055"},{"key":"e_1_2_11_34_1","doi-asserted-by":"publisher","DOI":"10.1177\/1534734620983181"},{"key":"e_1_2_11_35_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11065-020-09437-5"},{"key":"e_1_2_11_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mad.2021.111524"},{"key":"e_1_2_11_37_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00616.2021"},{"key":"e_1_2_11_38_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1002853"},{"key":"e_1_2_11_39_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0190699"},{"key":"e_1_2_11_40_1","doi-asserted-by":"publisher","DOI":"10.1002\/dmrr.3687"}],"container-title":["International Wound Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/iwj.70867","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/iwj.70867","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/iwj.70867","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,23]],"date-time":"2026-03-23T01:46:12Z","timestamp":1774230372000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/iwj.70867"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2,25]]},"references-count":39,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026,3]]}},"alternative-id":["10.1111\/iwj.70867"],"URL":"https:\/\/doi.org\/10.1111\/iwj.70867","archive":["Portico"],"relation":{},"ISSN":["1742-4801","1742-481X"],"issn-type":[{"value":"1742-4801","type":"print"},{"value":"1742-481X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,2,25]]},"assertion":[{"value":"2025-10-03","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-02-18","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-02-25","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70867"}}