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Additional objectives included assessing the relationship between pressure and healing, analysing the influence of the healthcare professional applying the bandage, and determining bandage stiffness. This prospective observational and multicentre study included 140 patients with active VLUs in Andalusia. Sub\u2010bandage pressures were measured at three anatomical points in the leg for 96\u2009h, under different positions and activities. The bandage application technique was standardised through specific training provided to advanced practice nurses. The initial pressures were higher than those recommended by guidelines, but showed a notable reduction within the first 24\u2009h, stabilising within therapeutic ranges for the remainder of the 96\u2010h study period. Most systems showed low dynamic and static stiffness. No significant pressure differences were found attributable to the nurses or the location of the injury. The observed pressure dynamics, initially high, with a subsequent drop and final stabilisation, suggest a high material settlement or application to compensate for the expected loss. The sustained pressure stability confirms the effectiveness of the systems over 96\u2009h.<\/jats:p>","DOI":"10.1111\/iwj.70868","type":"journal-article","created":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T06:19:43Z","timestamp":1773728383000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Temporal Assessment of Pressure and Stiffness in Compression Therapy for Venous Leg Ulcers: Implications for Clinical Optimization"],"prefix":"10.1111","volume":"23","author":[{"given":"Juan Francisco Jim\u00e9nez","family":"Garc\u00eda","sequence":"first","affiliation":[{"name":"Advanced Practice Nurse in Complex Chronic Wounds  Almeria Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-2826-1478","authenticated-orcid":false,"given":"Mar\u00eda Piedad Garc\u00eda","family":"Ru\u00edz","sequence":"additional","affiliation":[{"name":"Advanced Practice Nurse in Complex 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