{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,25]],"date-time":"2026-05-25T04:05:49Z","timestamp":1779681949835,"version":"3.53.1"},"reference-count":19,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,4,26]],"date-time":"2026-04-26T00:00:00Z","timestamp":1777161600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,4,26]],"date-time":"2026-04-26T00:00:00Z","timestamp":1777161600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["International Wound Journal"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Complex perianal fistulas are difficult to treat because of high recurrence rates and the need to preserve sphincter function. Negative pressure wound therapy (NPWT) improves healing in complex wounds, but its role in perianal fistula surgery is not well defined. This case series evaluated the feasibility, safety and early clinical outcomes of NPWT following surgical excision of complex perianal fistula tracts. A retrospective case series was conducted including eight adults with high or otherwise complex cryptoglandular perianal fistulas treated by surgical debridement followed by portable NPWT. Outcomes assessed were time to epithelialisation, symptom resolution, recurrence, complications and NPWT\u2010related technical issues and refinements. Seven of eight patients achieved complete epithelialisation of the perianal wound after NPWT. One patient developed recurrence and required ongoing seton drainage. Over the course of the series, optimisation of sealing, sponge contouring and use of a bridge technique improved dressing reliability and wound progression. No NPWT device\u2010related adverse events were observed. NPWT appears to be a feasible, well tolerated adjunct to surgery for complex cryptoglandular perianal fistulas, with high early healing rates and no device complications in this small series. Larger prospective studies are warranted to confirm efficacy and define optimal technical parameters.<\/jats:p>","DOI":"10.1111\/iwj.70920","type":"journal-article","created":{"date-parts":[[2026,4,27]],"date-time":"2026-04-27T02:55:21Z","timestamp":1777258521000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Negative Pressure Wound Therapy for Complex Perianal Fistulas: A Case Series"],"prefix":"10.1111","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-0550-774X","authenticated-orcid":false,"given":"Ariella Edina","family":"Kondor","sequence":"first","affiliation":[{"name":"Department of Surgery University of Pecs Medical School  P\u00e9cs Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jozsef","family":"Baracs","sequence":"additional","affiliation":[{"name":"Department of Surgery University of Pecs Medical School  P\u00e9cs Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Varga","sequence":"additional","affiliation":[{"name":"Department of Surgery University of Pecs Medical School  P\u00e9cs Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yashwanth Sudhendra","family":"Gowda","sequence":"additional","affiliation":[{"name":"Department of Surgery University of Pecs Medical School  P\u00e9cs Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elisabeth","family":"Garcia","sequence":"additional","affiliation":[{"name":"Department of Surgery University of Pecs Medical School  P\u00e9cs Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Halvax","sequence":"additional","affiliation":[{"name":"Department of Surgery University of Pecs Medical School  P\u00e9cs Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andras","family":"Vereczkei","sequence":"additional","affiliation":[{"name":"Department of Surgery University of Pecs Medical School  P\u00e9cs Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,4,26]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1177\/000313480807401008"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000637\u2010199706000\u201000001"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000637\u2010199706000\u201000002"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0007\u20101226(97)91369\u20102"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/iwj.12170"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1055\/s\u20100041\u20101731792"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.burns.2021.02.012"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.21037\/apm\u201021\u20102476"},{"issue":"1","key":"e_1_2_10_10_1","first-page":"77","article-title":"Benefits of Negative Pressure Wound Therapy in Skin Grafts: Systematic Review and Meta\u2010Analysis","volume":"51","author":"SYC L.","year":"2025","journal-title":"Burns"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/iwj.12492"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamasurg.2018.3467"},{"issue":"2","key":"e_1_2_10_13_1","first-page":"184","article-title":"Incisional Negative\u2010Pressure Wound Therapy: Recent RCTs and Evidence Synthesis\u2014Review of iNPWT for Prevention of Surgical Site Infection","volume":"6","author":"Groenen H.","year":"2023","journal-title":"Journal of Plastic, Reconstructive & Aesthetic Surgery"},{"issue":"2","key":"e_1_2_10_14_1","doi-asserted-by":"crossref","first-page":"S4","DOI":"10.12968\/bjon.2015.24.2.98","article-title":"A Portable, Disposable System for Negative\u2010Pressure Wound Therapy","volume":"24","author":"Brandon T.","year":"2015","journal-title":"British Journal of Nursing"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.12968\/jowc.2024.0033"},{"issue":"6","key":"e_1_2_10_16_1","first-page":"801","article-title":"The Application of Incisional Negative Pressure Wound Therapy for Perineal Wounds: A Systematic Review","volume":"15","author":"Cahill R. A.","year":"2018","journal-title":"International Wound Journal"},{"issue":"5","key":"e_1_2_10_17_1","first-page":"1401","article-title":"Incisional Negative Pressure Wound Therapy to Reduce Perineal Wound Complications After Abdominoperineal Resection: A Prospective Study","volume":"17","author":"Kaneko T.","year":"2020","journal-title":"International Wound Journal"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.3390\/jpm12101695"},{"key":"e_1_2_10_19_1","article-title":"Negative Pressure Wound Therapy and Split Thickness Skin Graft Aided the Healing of Extensive Perineum Necrotizing Fasciitis Without Faecal Diversion: A Case Report","volume":"18","author":"Tian Y.","year":"2019","journal-title":"BMC Surgery"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.12968\/jowc.2022.31.6.456"}],"container-title":["International Wound Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/iwj.70920","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/iwj.70920","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/iwj.70920","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,25]],"date-time":"2026-05-25T03:48:21Z","timestamp":1779680901000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/iwj.70920"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,26]]},"references-count":19,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2026,5]]}},"alternative-id":["10.1111\/iwj.70920"],"URL":"https:\/\/doi.org\/10.1111\/iwj.70920","archive":["Portico"],"relation":{},"ISSN":["1742-4801","1742-481X"],"issn-type":[{"value":"1742-4801","type":"print"},{"value":"1742-481X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4,26]]},"assertion":[{"value":"2025-12-04","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-04-07","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-04-26","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70920"}}